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中国上海老年残疾人群慢性肾脏病的患病率及相关危险因素:一项横断面研究

Prevalence and associated risk factors for chronic kidney disease in the elderly physically disabled population in Shanghai, China: a cross-sectional study.

作者信息

Wu Hengjing, Li Yao, Ren Longbing, Li Jue, Wang Yiyan, Jiang Chenghua, Wu Jing

机构信息

Clinical Center for Intelligent Rehabilitation Research, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University, Shanghai, 201619, China.

China Center for Health Development Studies, Peking University, Beijing, 100091, China.

出版信息

BMC Public Health. 2023 Oct 12;23(1):1987. doi: 10.1186/s12889-023-16455-4.

Abstract

BACKGROUND

The global prevalence of chronic kidney disease (CKD) in the general population is relatively clear. Our previous study showed that elderly individuals who are physically disabled are more likely to experience kidney function impairment, and the main purpose of this study was to determine the prevalence and risk factors associated with CKD in elderly patients with physical disabilities.

METHODS

A total of 2679 elderly individuals with physical disabilities from the 2018 Shanghai Disability Health Survey were screened to calculate the prevalence of CKD. Multiple logistic regression was performed to identify the factors associated with CKD. Detailed subgroup analyses of disability level were also conducted.

RESULTS

We confirmed CKD in 287 of 2679 (10.7%) participants. Female sex, age, history of hypertension, red blood cell count, albumin, urea, and uric acid (UA) were independently correlated with CKD. Age and UA abnormalities were common risk factors for different levels of disabilities.

CONCLUSION

The prevalence of CKD is higher in the mild level of older physically handicapped individuals. Age and the level of UA should also be considered in this population. The preventive strategies for patients with two levels of elderly disability should have different focuses.

摘要

背景

普通人群中慢性肾脏病(CKD)的全球患病率相对明确。我们之前的研究表明,身体残疾的老年人更易出现肾功能损害,本研究的主要目的是确定身体残疾老年患者中CKD的患病率及相关危险因素。

方法

对2018年上海残疾健康调查中的2679名身体残疾老年人进行筛查,以计算CKD的患病率。进行多因素逻辑回归以确定与CKD相关的因素。还对残疾程度进行了详细的亚组分析。

结果

2679名参与者中有287名(10.7%)确诊为CKD。女性、年龄、高血压病史、红细胞计数、白蛋白、尿素和尿酸(UA)与CKD独立相关。年龄和UA异常是不同残疾程度的常见危险因素。

结论

轻度身体残疾的老年个体中CKD患病率较高。该人群中还应考虑年龄和UA水平。针对两级老年残疾患者的预防策略应有不同侧重点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf27/10568763/bb3a310f224b/12889_2023_16455_Fig1_HTML.jpg

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