Department of Rehabilitation, Kitakyushu Municipal Medical Center, Kitakyushu, Japan.
Faculty of Medical Science, Nagoya Women's University, Nagoya, Japan.
Nagoya J Med Sci. 2023 Aug;85(3):518-527. doi: 10.18999/nagjms.85.3.518.
Frailty is considered one of the most important indicators of a patient's general condition. However, only a few studies have investigated the association between preoperative frailty and postoperative complications in pancreatic cancer. Therefore, this study aimed to examine this association in patients with pancreatic cancer. We retrospectively reviewed 52 consecutive patients who underwent pancreatectomy for pancreatic cancer between July 2019 and March 2021. Patients were classified into two groups according to the presence of postoperative complications. Their characteristics and clinical parameters, including physical function, were analyzed. Patients with postoperative complications had a higher prevalence of frailty (58.8% vs 14.3%, = 0.003) and a shorter 6-min walk distance (380 m vs 436 m, = 0.020) than those without postoperative complications. Logistic regression analysis identified preoperative frailty as the only independent risk factor for complications after pancreatectomy ( = 0.002). Preoperative frailty is associated with postoperative complications of pancreatectomy. Since preoperative frailty can be easily evaluated, it is a useful predictor of postoperative complications after pancreatectomy.
衰弱被认为是患者一般状况的最重要指标之一。然而，只有少数研究调查了胰腺癌患者术前衰弱与术后并发症之间的关系。因此，本研究旨在研究胰腺癌患者的这种相关性。我们回顾性分析了 2019 年 7 月至 2021 年 3 月间连续 52 例行胰腺切除术治疗胰腺癌的患者。根据术后并发症的存在将患者分为两组。分析了患者的特征和临床参数，包括身体功能。与无术后并发症的患者相比，术后并发症患者衰弱的发生率更高（58.8%比 14.3%，= 0.003），6 分钟步行距离更短（380 m 比 436 m，= 0.020）。Logistic 回归分析确定术前衰弱是胰腺切除术后并发症的唯一独立危险因素（= 0.002）。术前衰弱与胰腺切除术后并发症相关。由于术前衰弱可以很容易地评估，因此它是胰腺切除术后并发症的有用预测指标。
