Patel Sima, Maria-Rios Jose, Parikh Amay, Okorie Okorie Nduka
Department of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA.
Division of Neurocritical Care, Department of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA.
Int J Emerg Med. 2023 Oct 13;16(1):72. doi: 10.1186/s12245-023-00540-x.
Elevated intracranial pressure is a devastating complication of catastrophic brain injury. Intracranial hypertension is commonly seen in neurologic injury secondary to traumatic brain injuries. Uncontrolled pressures can lead to permanent neurologic damage, but acute medical management is often overlooked when pursuing surgical management options that may not always be indicated.
Traumatic brain injury is the leading cause of death in patients with severe neurologic injury. Diagnosing elevated intracranial pressures is imperative in initiating prompt treatment to reduce secondary central nervous system injury, morbidity, and mortality. Although the initial injury to the brain is typically irreversible, intracranial pressure control can assist in salvaging the remaining brain tissue from additional damage. We will discuss the initial medical and surgical management of traumatic brain injury to prevent further neurologic deterioration and reduce mortality.
Recent literature has reported several methods to detect elevated intracranial pressure easily and studies describing multiple treatment modalities. These investigations suggest that early detection and timely treatment of intracranial hypertension are beneficial in reducing mortality.
颅内压升高是灾难性脑损伤的一种毁灭性并发症。颅内高压常见于创伤性脑损伤继发的神经损伤。压力控制不佳可导致永久性神经损伤,但在寻求可能并非总是必要的手术治疗方案时,急性药物治疗往往被忽视。
创伤性脑损伤是严重神经损伤患者死亡的主要原因。诊断颅内压升高对于启动及时治疗以减少继发性中枢神经系统损伤、发病率和死亡率至关重要。虽然脑部的初始损伤通常是不可逆的,但控制颅内压有助于挽救剩余脑组织免受进一步损伤。我们将讨论创伤性脑损伤的初始药物和手术治疗,以防止进一步的神经功能恶化并降低死亡率。
最近的文献报道了几种易于检测颅内压升高的方法以及描述多种治疗方式的研究。这些研究表明,早期发现和及时治疗颅内高压有助于降低死亡率。