MED Institute Inc., West Lafayette, IN, United States of America.
Abbott Laboratories, Sylmar, CA, United States of America.
Biomed Phys Eng Express. 2023 Oct 26;9(6). doi: 10.1088/2057-1976/ad0398.
. The goal of this study was to develop and validate a computational model that can accurately predict the influence of flow on the temperature rise near a peripheral vascular stent during magnetic resonance imaging (MRI).. Computational modeling and simulation of radio frequency (RF) induced heating of a vascular stent during MRI at 3.0 T was developed and validated with flow phantom experiments. The maximum temperature rise of the stent was measured as a function of physiologically relevant flow rates.. A significant difference was not identified between the experiment and simulation (P > 0.05). The temperature rise of the stent during MRI was over 10 °C without flow, and was reduced by 5 °C with a flow rate of only 58 ml min, corresponding to a reduction of CEMfrom 45 min to less than 1 min.. The computer model developed in this study was validated with experimental measurements, and accurately predicted the influence of flow on the RF-induced temperature rise of a vascular stent during MRI. Furthermore, the results of this study demonstrate that relatively low flow rates significantly reduce the temperature rise of a stent and the surrounding medium during RF-induced heating under typical scanning power and physiologically relevant conditions.
. 本研究的目的是开发和验证一种计算模型，该模型能够准确预测磁共振成像（MRI）过程中血流对周围血管支架附近温升的影响。. 使用流态模型实验对 3.0T 磁共振成像过程中血管支架射频（RF）加热的计算模型和模拟进行了开发和验证。测量了支架最大温升作为与生理相关流速的函数。. 实验和模拟之间没有发现显著差异（P > 0.05）。无血流时支架在 MRI 过程中的温升超过 10°C，仅 58ml/min 的流速就降低了 5°C，相应地将 CEM 从 45 分钟减少到不到 1 分钟。. 本研究中开发的计算机模型通过实验测量进行了验证，并准确预测了血流对 MRI 过程中血管支架 RF 诱导温升的影响。此外，本研究的结果表明，在典型的扫描功率和生理相关条件下，相对较低的流速可显著降低 RF 诱导加热过程中支架和周围介质的温升。
