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计算模型研究血流对 MRI 中外周血管支架射频加热的热效应。

Computational modeling of the thermal effects of flow on radio frequency-induced heating of peripheral vascular stents during MRI.

机构信息

MED Institute Inc., West Lafayette, IN, United States of America.

Abbott Laboratories, Sylmar, CA, United States of America.

出版信息

Biomed Phys Eng Express. 2023 Oct 26;9(6). doi: 10.1088/2057-1976/ad0398.

Abstract

. The goal of this study was to develop and validate a computational model that can accurately predict the influence of flow on the temperature rise near a peripheral vascular stent during magnetic resonance imaging (MRI).. Computational modeling and simulation of radio frequency (RF) induced heating of a vascular stent during MRI at 3.0 T was developed and validated with flow phantom experiments. The maximum temperature rise of the stent was measured as a function of physiologically relevant flow rates.. A significant difference was not identified between the experiment and simulation (P > 0.05). The temperature rise of the stent during MRI was over 10 °C without flow, and was reduced by 5 °C with a flow rate of only 58 ml min, corresponding to a reduction of CEMfrom 45 min to less than 1 min.. The computer model developed in this study was validated with experimental measurements, and accurately predicted the influence of flow on the RF-induced temperature rise of a vascular stent during MRI. Furthermore, the results of this study demonstrate that relatively low flow rates significantly reduce the temperature rise of a stent and the surrounding medium during RF-induced heating under typical scanning power and physiologically relevant conditions.

摘要

. 本研究的目的是开发和验证一种计算模型,该模型能够准确预测磁共振成像(MRI)过程中血流对周围血管支架附近温升的影响。. 使用流态模型实验对 3.0T 磁共振成像过程中血管支架射频(RF)加热的计算模型和模拟进行了开发和验证。测量了支架最大温升作为与生理相关流速的函数。. 实验和模拟之间没有发现显著差异(P > 0.05)。无血流时支架在 MRI 过程中的温升超过 10°C,仅 58ml/min 的流速就降低了 5°C,相应地将 CEM 从 45 分钟减少到不到 1 分钟。. 本研究中开发的计算机模型通过实验测量进行了验证,并准确预测了血流对 MRI 过程中血管支架 RF 诱导温升的影响。此外,本研究的结果表明,在典型的扫描功率和生理相关条件下,相对较低的流速可显著降低 RF 诱导加热过程中支架和周围介质的温升。

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