From the Department of Infection (Zhang), Department of Gastroenterology (Ma), Department of Geriatrics (Cai), Gaochun People's Hospital, Nanjing, and From the Department of Gastroenterology (Qiao), Suzhou Ninth People's Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
Neurosciences (Riyadh). 2023 Oct;28(4):270-272. doi: 10.17712/nsj.2023.4.202300133.
Hemorrhagic fever with renal syndrome (HFRS) and reversible splenial lesion syndrome are both considered uncommon conditions relatively rare. Fever, hemorrhage, and acute kidney injury are the prevailing symptoms frequently observed in cases of HFRS. We describe a case of a middle-aged man who had been hospitalized with fever and acute neurological symptoms. His main symptom was recurrent dizziness. Cranial computed tomography (CT) did not reveal any obvious lesions, such as encephalorrhagia or infarctions. The splenium of corpus callosum showed hyperintensity on brain magnetic resonance imaging (MRI), which is in line with the characteristic radiographic observations of reversible splenial lesion syndrome (RESLES). Further analyses revealed that the patient's platelet counts had decreased to 7×10/L while hemorrhagic fever antibodies were positive. Eventually, the patient was diagnosed with HFRS and exhibited clinical improvements after active treatment.
肾综合征出血热（HFRS）和可逆性胼胝体压部病变综合征（RESLES）均属于相对罕见的疾病。HFRS 常以发热、出血和急性肾损伤为主要表现，发热伴急性神经系统症状的中年男性患者，以反复头晕为主要表现，头颅 CT 未见出血或梗死病灶，头颅磁共振成像（MRI）显示胼胝体压部高信号，符合 RESLES 的特征性影像学表现。进一步分析提示患者血小板计数下降至 7×10^9/L，出血热抗体阳性，最终诊断为 HFRS，经积极治疗后患者病情好转。
