Department of Lymphoma & Hematology, The Affiliated Tumor Hospital of Xiangya Medical School, Central South University, Changsha, Hunan, China.
Department of Histology and Embryology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China.
Hum Vaccin Immunother. 2023 Dec 15;19(3):2267865. doi: 10.1080/21645515.2023.2267865. Epub 2023 Oct 16.
CAR-T cell therapy, a novel therapeutic approach that has attracted much attention in the field of cancer treatment at present, has become the subject of many studies and has shown great potential in the treatment of hematological malignancies, such as leukemia and lymphoma. This study aims to analyze the characteristics of articles published on CAR-T cell therapy in the lymphoma field and explore the existing hotspots and frontiers. The relevant articles published from 2013 to 2022 were retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, Bibliometric online analysis platform, Microsoft Excel, and R software were used for bibliometric analysis and visualization. The number of publications related to the research has been increasing year by year, including 1023 articles and 760 reviews from 62 countries and regions, 2092 institutions, 1040 journals, and 8727 authors. The United States, China, and Germany are the main publishing countries in this research field. The top 10 institutions are all from the United States, the journal with the highest impact factor is , the author with the most publications is Frederick L Locke, and the most influential author is Carl H June. The top three keywords are "Lymphoma," "Immunotherapy," and "Therapy." "Maude (2014)" is the most cited and strongest burstiness reference over the past decade. This study provides a comprehensive bibliometric analysis of CAR-T cell therapy in lymphoma, which can help researchers understand the current research hotspots in this field, explore potential research directions, and identify future development trends.
嵌合抗原受体 T 细胞疗法(CAR-T 细胞疗法)是目前癌症治疗领域备受关注的一种新型治疗方法,已成为许多研究的主题,并在治疗血液系统恶性肿瘤(如白血病和淋巴瘤)方面显示出巨大潜力。本研究旨在分析淋巴瘤领域中 CAR-T 细胞疗法相关文章的特征,并探讨现有热点和前沿。从 2013 年至 2022 年,从 Web of Science 核心合集检索到相关文章。使用 CiteSpace、VOSviewer、文献计量在线分析平台、Microsoft Excel 和 R 软件进行文献计量分析和可视化。与该研究相关的出版物数量逐年增加,包括来自 62 个国家和地区的 1023 篇文章和 760 篇综述,来自 2092 个机构、1040 种期刊和 8727 位作者。美国、中国和德国是该研究领域的主要出版国。排名前 10 的机构均来自美国,影响因子最高的期刊是 ,发文量最多的作者是 Frederick L Locke,最有影响力的作者是 Carl H June。排名前三的关键词是“Lymphoma”(淋巴瘤)、“Immunotherapy”(免疫疗法)和“Therapy”(治疗)。过去十年中,“Maude (2014)”是被引最多且突现强度最强的参考文献。本研究对淋巴瘤中的 CAR-T 细胞疗法进行了全面的文献计量分析,有助于研究人员了解该领域当前的研究热点,探索潜在的研究方向,并识别未来的发展趋势。
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