Sarvepalli Sai Suseel, Vemula Shree Laya, Aramadaka Saikumar, Mannam Raam, Sankara Narayanan Rajagopal, Bansal Arpit, Yanamaladoddi Vishnu R
Department of Research, Narayana Medical College, Nellore, IND.
Department of Research, Anam Chenchu Subba Reddy (ACSR) Government Medical College, Nellore, IND.
Cureus. 2023 Sep 15;15(9):e45279. doi: 10.7759/cureus.45279. eCollection 2023 Sep.
Irritable bowel syndrome (IBS) plagues nearly a fifth of the general population. It is a chronic illness that can significantly lower quality of life (QoL) and work productivity. The relationship between diet and the functional gastrointestinal (GI) symptoms present in IBS is gaining more and more attention. In addition to being a factor in the pathophysiology of IBS, diet also has a significant impact on symptoms and overall well-being. Recent research has also shown that short-chain fermentable carbohydrates increase colonic gas production and small intestine water volume, which in turn causes functional GI symptoms in those with visceral hypersensitivity. This review article has consolidated various studies highlighting the association between certain foods and the pathophysiology of IBS. It has also talked about how restricting certain food items from the diet of affected individuals can relieve symptoms and in some cases can be more effective than pharmacotherapy. Although the low reduced fermentable oligosaccharide, disaccharide, monosaccharide, and polyol (FODMAP) diet (LFD) is a well-known method of treating IBS symptoms, over a third of individuals do not benefit from it. This article has also discussed the effectiveness and applicability of the LFD compared to other dietary therapies for the long-term management of IBS.
肠易激综合征（IBS）困扰着近五分之一的普通人群。它是一种慢性疾病，会显著降低生活质量（QoL）和工作效率。饮食与IBS中出现的功能性胃肠道（GI）症状之间的关系越来越受到关注。饮食不仅是IBS病理生理学的一个因素，对症状和整体健康状况也有重大影响。最近的研究还表明，短链可发酵碳水化合物会增加结肠气体产生和小肠水量，进而在那些有内脏高敏感性的人群中引发功能性GI症状。这篇综述文章整合了各项研究，突出了某些食物与IBS病理生理学之间的关联。它还探讨了从受影响个体的饮食中限制某些食物如何能够缓解症状，并且在某些情况下比药物治疗更有效。尽管低可发酵寡糖、双糖、单糖和多元醇（FODMAP）饮食（LFD）是一种治疗IBS症状的知名方法，但超过三分之一的个体并未从中受益。本文还讨论了LFD与其他饮食疗法相比在IBS长期管理中的有效性和适用性。
