年轻和衰老的人二倍体成纤维细胞中热休克蛋白的诱导
Induction of heat shock proteins in young and senescent human diploid fibroblasts.
作者信息
Tsuji Y, Ishibashi S, Ide T
出版信息
Mech Ageing Dev. 1986 Oct;36(2):155-60. doi: 10.1016/0047-6374(86)90016-3.
PMID:3784628
Abstract
When human diploid fibroblasts, TIG-1, reached the end of their proliferative lifespan in vitro, they still could synthesize proteins with molecular weight of about 70,000, 85,000 and 116,000 following the heat shock at 46 degrees C for 10 min as well as young cells did so.
摘要
当人二倍体成纤维细胞TIG-1在体外达到其增殖寿命终点时，在46℃热休克10分钟后，它们仍能像年轻细胞一样合成分子量约为70000、85000和116000的蛋白质。
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