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[放射治疗对喉黏膜纤毛上皮功能的影响]

[Effect of radiotherapy on the function of the ciliated epithelium in the larynx].

作者信息

Deitmer T

出版信息

Laryngol Rhinol Otol (Stuttg). 1986 Sep;65(9):513-5.

PMID:3784733
Abstract

Five human larynges, obtained by surgery, were examined by light and electron microscopy and with an operating microscope, searching for signs of ciliary activity. In two larynges the mucociliary waves could be seen in the subglottic space, whereas a mucociliary transport could not be proved. Via light microscopy, fully ciliated epithelium was found in some cases, in other cases ciliated epithelium was seen only occasionally, whereas in some cases it was absent, substituted by squamous epithelium. The ciliary ultrastructure was normal. The author discusses whether the ciliated structure survives radiotherapy, or whether a regeneration occurs from untreated areas.

摘要

对通过手术获取的5个人类喉部进行了光学显微镜、电子显微镜检查,并使用手术显微镜寻找纤毛活动的迹象。在两个喉部中,可以在声门下间隙看到黏液纤毛波,但未能证实存在黏液纤毛运输。通过光学显微镜观察,在某些情况下发现了完全有纤毛的上皮,在其他情况下仅偶尔可见有纤毛的上皮,而在某些情况下则不存在,被鳞状上皮所取代。纤毛的超微结构正常。作者讨论了有纤毛结构在放疗后是否存活,或者是否从未经治疗的区域发生再生。

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