Suppr超能文献

德国扁桃体炎指南对复发性急性扁桃体炎患者扁桃体切除术适应证的影响:一项基于人群的研究。

Effect of the German tonsillitis guideline on indication for tonsil surgery in patients with recurrent acute tonsillitis: a population-based study.

机构信息

Department of Otorhinolaryngology, Jena University Hospital, Jena, Germany.

Department of Otorhinolaryngology, Zentralklinikum, Suhl, Germany.

出版信息

Sci Rep. 2023 Oct 17;13(1):17612. doi: 10.1038/s41598-023-44661-y.

Abstract

Evidence-based indication for tonsil surgery in patients with recurrent acute tonsillitis (RAT) is an ongoing matter of debate. Since introduction of the German tonsillitis guideline in 2015, the indication criteria for tonsil surgery have become much stricter. It is unclear, if this has changed the indication policy. A retrospective population-based study was performed including all 1398 patients with RAT admitted for tonsil surgery in all Thuringian hospitals in 2011, 2015, and 2019. Changes over the years concerning patients' characteristics, number of tonsillitis episodes in the last 12 months treated with antibiotics (T12), and decision for tonsillectomy or tonsillotomy were analyzed using univariable and multivariable statistics. The surgical rates decreased from 28.56/100,000 population in 2011 to 23.57 in 2015, and to 11.60 in 2019. The relative amount of patients with ≥ 6 T12 increased from 14.1% in 2011 over 13.3% in 2015 to 35.9% in 2019. Most patients received a tonsillectomy (98% of all surgeries). Decision for tonsillotomy was seldom (1.2%). Multinomial logistic regression analysis with the year 2011 as reference showed that compared to the year 2015, the age of the patients undergoing surgery increased in 2015 (Odds ratio [OR] = 1.024; 95% confidence interval [CI] = 1.014-1.034; p < 0.001), and also in 2019 (OR 1.030: CI 1.017-1.043; p < 0.001). Compared to 2011, the number T12 was not higher in 2015, but in 2019 (OR 1.273; CI 1.185-1.367; p < 0.001). Stricter rules led to lower tonsil surgery rates but to a higher proportion of patients with ≥ 6 T12 before surgery. Tonsillectomy remained the dominating technique.

摘要

在复发性急性扁桃体炎(RAT)患者中进行扁桃体手术的循证指征一直是一个有争议的问题。自 2015 年德国扁桃体炎指南出台以来,扁桃体手术的指征标准变得更加严格。目前尚不清楚这是否改变了手术指征政策。本研究回顾性分析了 2011 年、2015 年和 2019 年在图林根州所有医院接受扁桃体手术的 1398 例 RAT 患者的人口统计学资料,分析了患者特征、过去 12 个月中抗生素治疗的扁桃体炎发作次数(T12)以及扁桃体切除术或扁桃体切开术的决策变化。使用单变量和多变量统计方法分析了多年来的变化。手术率从 2011 年的 28.56/100,000 人下降到 2015 年的 23.57 人,再到 2019 年的 11.60 人。过去 12 个月中 T12 发作次数≥6 次的患者比例从 2011 年的 14.1%上升到 2015 年的 13.3%,再到 2019 年的 35.9%。大多数患者接受了扁桃体切除术(所有手术的 98%)。很少进行扁桃体切开术(占所有手术的 1.2%)。以 2011 年为参考的多项逻辑回归分析显示,与 2015 年相比,2015 年接受手术的患者年龄更大(优势比[OR]为 1.024;95%置信区间[CI]为 1.014-1.034;p<0.001),2019 年也是如此(OR 为 1.030;CI 为 1.017-1.043;p<0.001)。与 2011 年相比,2015 年 T12 并没有增加,但 2019 年增加了(OR 为 1.273;CI 为 1.185-1.367;p<0.001)。更严格的规则导致扁桃体手术率下降,但手术前 T12 发作次数≥6 次的患者比例更高。扁桃体切除术仍然是主要的手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547c/10582004/f2127e51a8c9/41598_2023_44661_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验