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扁桃体切除术适应证的发生率和基于证据的手术频率:初级保健电子记录的 12 年回顾性队列研究。

Incidence of indications for tonsillectomy and frequency of evidence-based surgery: a 12-year retrospective cohort study of primary care electronic records.

机构信息

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

出版信息

Br J Gen Pract. 2019 Jan;69(678):e33-e41. doi: 10.3399/bjgp18X699833. Epub 2018 Nov 5.

Abstract

BACKGROUND

Neither the incidence of indications for childhood tonsillectomy nor the proportion of tonsillectomies that are evidence-based is known.

AIM

To determine the incidence of indications for tonsillectomy in UK children, and the proportion of tonsillectomies meeting evidence-based criteria.

DESIGN AND SETTING

A retrospective cohort study of electronic medical records of children aged 0-15 years registered with 739 UK general practices contributing to a research database.

METHOD

Children with recorded indications for tonsillectomy were identified from electronic medical records. Evidence-based indications included documented sore throats of sufficient frequency and severity (Paradise criteria); periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome (PFAPA); or tonsillar tumour. Other indications were considered non-evidence-based. The numbers of children subsequently undergoing tonsillectomy was then identified. The numbers with evidence-based and non-evidence-based indications for surgery among children who had undergone tonsillectomy were determined.

RESULTS

The authors included 1 630 807 children followed up for 7 200 159 person-years between 2005 and 2016. Incidence of evidence-based indications for tonsillectomy was 4.2 per 1000 person years; 13.6% (2144/15 760) underwent tonsillectomy. Incidence of childhood tonsillectomy was 2.5 per 1000 person years; 11.7% (2144/18 281) had evidence-based indications, almost all with Paradise criteria. The proportion of evidence-based tonsillectomies was unchanged over 12 years. Most childhood tonsillectomies followed non-evidence-based indications: five to six sore throats (12.4%) in 1 year, two to four sore throats (44.6%) in 1 year, sleep disordered breathing (12.3%), or obstructive sleep apnoea (3.9%).

CONCLUSION

In the UK, few children with evidence-based indications undergo tonsillectomy and seven in eight of those who do (32 500 of 37 000 annually) are unlikely to benefit.

摘要

背景

儿童扁桃体切除术适应证的发生率以及基于证据的扁桃体切除术的比例均不清楚。

目的

确定英国儿童扁桃体切除术适应证的发生率以及符合基于证据的标准的扁桃体切除术的比例。

设计和设置

对参与研究数据库的 739 家英国普通实践注册的 0-15 岁儿童的电子病历进行回顾性队列研究。

方法

从电子病历中确定有记录的扁桃体切除术适应证的儿童。基于证据的适应证包括记录有足够频率和严重程度的咽痛(Paradise 标准)、周期性发热、口疮性口炎、咽炎和颈淋巴结炎综合征(PFAPA)或扁桃体肿瘤。其他适应证被认为是非基于证据的。随后确定进行扁桃体切除术的儿童数量。在进行扁桃体切除术的儿童中,确定具有基于证据和非基于证据的手术适应证的儿童数量。

结果

作者纳入了 2005 年至 2016 年间随访 7 200 159 人年的 1 630 807 名儿童。扁桃体切除术基于证据的适应证发生率为每 1000 人年 4.2 例;13.6%(2144/15760)接受了扁桃体切除术。儿童扁桃体切除术的发生率为每 1000 人年 2.5 例;11.7%(2144/18281)有基于证据的适应证,几乎全部符合 Paradise 标准。12 年来,基于证据的扁桃体切除术比例没有变化。大多数儿童扁桃体切除术遵循非基于证据的适应证:1 年内 5-6 次咽痛(12.4%)、1 年内 2-4 次咽痛(44.6%)、睡眠障碍性呼吸(12.3%)或阻塞性睡眠呼吸暂停(3.9%)。

结论

在英国,有基于证据的适应证的儿童中很少接受扁桃体切除术,而其中 8 个中有 7 个(每年 37000 例中的 32500 例)不太可能受益。

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