• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

3T 磁共振引导下腰椎和骶孔注射的临床疗效。

Clinical outcomes of 3T magnetic resonance imaging-guided lumbar and sacral foraminal injections.

机构信息

Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Division of Radiology, Geneva University Hospitals, Geneva, Switzerland.

出版信息

Neuroradiology. 2023 Dec;65(12):1793-1802. doi: 10.1007/s00234-023-03234-6. Epub 2023 Oct 17.

DOI:10.1007/s00234-023-03234-6
PMID:37848741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10654205/
Abstract

PURPOSE

This article evaluates the feasibility, safety, and efficacy of MRI-guided lumbar or sacral nerve root infiltration for chronic back pain. We compared the outcomes of our MRI-guided infiltrations with data from CT-guided infiltrations reported in the literature and explored the potential advantages of MRI guidance.

METHOD

Forty-eight MRI-guided nerve root infiltrations were performed using a 3 T MRI machine. The optimal needle path was determined using breathhold T2-weighted sequences, and the needle was advanced under interleaved guidance based on breathhold PD-weighted images. Pain levels were assessed using a numeric rating scale (NRS) before the procedure and up to 5 months after, during follow-up. Procedure success was evaluated by comparing patients' pain levels before and after the infiltration.

RESULTS

The MRI-guided infiltrations yielded pain reduction 1 week after the infiltration in 92% of cases, with an average NRS substantial change of 3.9 points. Pain reduction persisted after 5 months for 51% of procedures. No procedure-related complications occurred. The use of a 22G needle and reconstructed subtraction images from T2 FatSat sequences improved the workflow.

CONCLUSION

Our study showed that MRI-guided nerve root infiltration is a feasible, safe, and effective treatment option for chronic back pain. Precise positioning of the needle tip and accurate distribution of the injected solution contributed to the effectiveness of MRI-guided infiltration, which appeared to be as accurate as CT-guided procedures. Further research is needed to explore the potential benefits of metal artifact reduction sequences to optimize chronic back pain management.

摘要

目的

本文评估了 MRI 引导下腰椎或骶神经根浸润术治疗慢性腰痛的可行性、安全性和疗效。我们将我们的 MRI 引导下浸润术的结果与文献中报告的 CT 引导下浸润术的数据进行了比较,并探讨了 MRI 引导的潜在优势。

方法

使用 3T MRI 机进行了 48 例 MRI 引导下的神经根浸润术。使用屏气 T2 加权序列确定最佳进针路径,根据屏气 PD 加权图像进行交错引导进针。在术前和术后 5 个月的随访期间,使用数字评分量表(NRS)评估疼痛程度。通过比较浸润前后患者的疼痛程度来评估手术成功率。

结果

MRI 引导下的浸润术在 92%的病例中在浸润后 1 周内减轻了疼痛,平均 NRS 显著变化为 3.9 分。51%的病例在 5 个月后仍有疼痛减轻。无手术相关并发症发生。使用 22G 针和 T2 FatSat 序列重建的减影图像改善了工作流程。

结论

我们的研究表明,MRI 引导下神经根浸润术是治疗慢性腰痛的一种可行、安全且有效的治疗选择。针尖的精确定位和注入溶液的准确分布有助于 MRI 引导下浸润术的有效性,其准确性似乎与 CT 引导下的程序相当。需要进一步研究来探讨金属伪影减少序列的潜在益处,以优化慢性腰痛的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/f60b07786b91/234_2023_3234_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/2148853086f1/234_2023_3234_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/c34b4e415163/234_2023_3234_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/038e160395d9/234_2023_3234_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/48ac9ea0f778/234_2023_3234_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/f43e72650707/234_2023_3234_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/c15e1e4e2232/234_2023_3234_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/f60b07786b91/234_2023_3234_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/2148853086f1/234_2023_3234_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/c34b4e415163/234_2023_3234_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/038e160395d9/234_2023_3234_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/48ac9ea0f778/234_2023_3234_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/f43e72650707/234_2023_3234_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/c15e1e4e2232/234_2023_3234_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cd/10654205/f60b07786b91/234_2023_3234_Fig7_HTML.jpg

相似文献

1
Clinical outcomes of 3T magnetic resonance imaging-guided lumbar and sacral foraminal injections.3T 磁共振引导下腰椎和骶孔注射的临床疗效。
Neuroradiology. 2023 Dec;65(12):1793-1802. doi: 10.1007/s00234-023-03234-6. Epub 2023 Oct 17.
2
Magnetic resonance imaging-guided lumbar nerve root infiltrations: optimization of an in-house protocol.磁共振引导下腰椎神经根浸润术:内部方案的优化。
BMC Med Imaging. 2021 Jul 12;21(1):110. doi: 10.1186/s12880-021-00641-0.
3
MRI-guided periradicular nerve root infiltration therapy in low-field (0.23-T) MRI system using optical instrument tracking.在低场(0.23-T)MRI系统中使用光学仪器跟踪进行MRI引导下的根尖神经根浸润治疗。
Eur Radiol. 2002 Jun;12(6):1331-7. doi: 10.1007/s00330-002-1397-z. Epub 2002 Mar 20.
4
Cost comparison of nerve root infiltration of the lumbar spine under MRI and CT guidance.MRI 和 CT 引导下腰椎神经根浸润的成本比较。
Eur Radiol. 2013 Jun;23(6):1487-94. doi: 10.1007/s00330-012-2757-y. Epub 2013 Jan 12.
5
CT-guided nucleoplasty with radiofrequency energy for the treatment of lumbar disk herniation.CT引导下射频能量髓核成形术治疗腰椎间盘突出症。
J Spinal Disord Tech. 2015 Feb;28(1):E9-16. doi: 10.1097/BSD.0000000000000132.
6
Symptomatic magnetic resonance imaging-confirmed lumbar disk herniation patients: a comparative effectiveness prospective observational study of 2 age- and sex-matched cohorts treated with either high-velocity, low-amplitude spinal manipulative therapy or imaging-guided lumbar nerve root injections.有症状且经磁共振成像确诊的腰椎间盘突出症患者:一项前瞻性观察性比较疗效研究,涉及两个年龄和性别匹配的队列,分别接受高速低幅脊柱推拿治疗或影像引导下腰椎神经根注射治疗。
J Manipulative Physiol Ther. 2013 May;36(4):218-25. doi: 10.1016/j.jmpt.2013.04.005. Epub 2013 May 22.
7
Real-time MR-guided lumbosacral periradicular injection therapy using an open 1.0-T MRI system: an outcome study.实时磁共振引导下腰骶部旁神经阻滞注射治疗:一项结局研究。
Invest Radiol. 2013 Jun;48(6):471-6. doi: 10.1097/RLI.0b013e31828362be.
8
Severity of foraminal lumbar stenosis and the relation to clinical symptoms and response to periradicular infiltration-introduction of the "melting sign".椎间孔型腰椎狭窄症的严重程度及其与临床症状的关系和对神经根周围浸润的反应-“熔化征”的介绍。
Spine J. 2018 Feb;18(2):294-299. doi: 10.1016/j.spinee.2017.07.176. Epub 2017 Jul 21.
9
Deep Learning Algorithm Trained on Lumbar Magnetic Resonance Imaging to Predict Outcomes of Transforaminal Epidural Steroid Injection for Chronic Lumbosacral Radicular Pain.基于腰椎磁共振成像的深度学习算法预测经椎间孔硬膜外类固醇注射治疗慢性腰骶神经根性疼痛的疗效。
Pain Physician. 2022 Nov;25(8):587-592.
10
CT-guided transforaminal epidural injections with local anesthetic, steroid, and tramadol for the treatment of persistent lumbar radicular pain.CT 引导下经椎间孔硬膜外注射局麻药、皮质类固醇和曲马多治疗持续性腰椎根性疼痛。
Pain Physician. 2012 Mar-Apr;15(2):153-9.

引用本文的文献

1
Real-Time MR-Guided Lumbosacral Periradicular Injection Therapy Using a 0.55 T MRI System: A Phantom Study.使用0.55 T磁共振成像系统进行实时磁共振引导下腰骶部神经根周围注射治疗:一项体模研究
Diagnostics (Basel). 2025 Jun 2;15(11):1413. doi: 10.3390/diagnostics15111413.

本文引用的文献

1
Sciatica. Management for family physicians.坐骨神经痛。家庭医生的管理方法。
J Family Med Prim Care. 2022 Aug;11(8):4174-4179. doi: 10.4103/jfmpc.jfmpc_1061_21. Epub 2022 Aug 30.
2
Magnetic resonance imaging-guided lumbar nerve root infiltrations: optimization of an in-house protocol.磁共振引导下腰椎神经根浸润术:内部方案的优化。
BMC Med Imaging. 2021 Jul 12;21(1):110. doi: 10.1186/s12880-021-00641-0.
3
Low back pain.下背痛。
Lancet. 2021 Jul 3;398(10294):78-92. doi: 10.1016/S0140-6736(21)00733-9. Epub 2021 Jun 8.
4
CT-Guided Caudal Epidural Infiltrations: A Technical Note.CT引导下尾侧硬膜外注射:技术说明
AJNR Am J Neuroradiol. 2021 Sep;42(9):E60-E61. doi: 10.3174/ajnr.A7178. Epub 2021 Jun 3.
5
Evidence-based treatment recommendations for neck and low back pain across Europe: A systematic review of guidelines.基于证据的欧洲颈腰痛治疗推荐:指南的系统评价。
Eur J Pain. 2021 Feb;25(2):275-295. doi: 10.1002/ejp.1679. Epub 2020 Nov 12.
6
Role of transforaminal epidural injections or selective nerve root blocks in the management of lumbar radicular syndrome - A narrative, evidence-based review.经椎间孔硬膜外注射或选择性神经根阻滞在腰椎神经根综合征治疗中的作用——一项基于证据的叙述性综述
J Clin Orthop Trauma. 2020 Sep-Oct;11(5):802-809. doi: 10.1016/j.jcot.2020.06.004. Epub 2020 Jun 26.
7
The Effectiveness of Lumbar Transforaminal Injection of Steroid for the Treatment of Radicular Pain: A Comprehensive Review of the Published Data.腰椎经皮穿刺注射类固醇治疗根性疼痛的疗效:已发表数据的综合评价。
Pain Med. 2020 Mar 1;21(3):472-487. doi: 10.1093/pm/pnz160.
8
Comparison of treatment outcomes in lumbar disc herniation patients treated with epidural steroid injections: interlaminar versus transforaminal approach.硬膜外类固醇注射治疗腰椎间盘突出症患者的疗效比较:椎间孔入路与经椎间孔入路。
Acta Radiol. 2020 Mar;61(3):361-369. doi: 10.1177/0284185119858681. Epub 2019 Jul 2.
9
Lumbar foraminal neuropathy: an update on non-surgical management.腰椎椎间孔性神经病变:非手术治疗的最新进展
Korean J Pain. 2019 Jul 1;32(3):147-159. doi: 10.3344/kjp.2019.32.3.147.
10
Fluoroscopically Guided Lumbar Transforaminal Epidural Steroid Injection: Procedural Technique.
Clin Spine Surg. 2018 Aug;31(7):297-299. doi: 10.1097/BSD.0000000000000627.