Cassileth B R, Lusk E J, Brown L L, Cross P A, Walsh W P, Hurwitz S
Med Pediatr Oncol. 1986;14(5):251-4. doi: 10.1002/mpo.2950140503.
We studied the mental health of 1,278 patients with cancer and 645 family members of patients with cancer to delineate clinical and demographic characteristics associated with poor psychological status. For both patients and their matched relatives, there was a direct relationship between poorer mental health scores and younger age. Highly significant age differences emerged as well for subscale scores of anxiety, depression, and general positive affect in patients, and for depression, emotional ties, and loss of control in relatives. Treatment status, performance status, and sex also contributed significantly to mental health scores. Patients at greatest risk for psychological problems are young, female, receiving palliative or active treatment as opposed to follow-up care, and symptomatic or not fully ambulatory. Clinicians should be alert to the potential for psychological problems among patients in these categories.
我们研究了1278名癌症患者以及645名癌症患者家属的心理健康状况，以确定与心理状态不佳相关的临床和人口统计学特征。对于患者及其匹配的亲属而言，心理健康得分越低与年龄越小呈直接关系。患者焦虑、抑郁和总体积极情绪分量表得分，以及亲属抑郁、情感纽带和失控感分量表得分也出现了显著的年龄差异。治疗状态、体能状态和性别对心理健康得分也有显著影响。心理问题风险最高的患者是年轻女性，接受姑息治疗或积极治疗而非随访护理，且有症状或行动不便。临床医生应警惕这些类别患者出现心理问题的可能性。
