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金丝桃苷对氧化应激诱导的人类疾病的潜在影响：综述

Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review.

作者信息

Wang Kaiyang, Zhang Huhai, Yuan Lie, Li Xiaoli, Cai Yongqing

机构信息

Department of Pharmacy, Daping Hospital, Army Medical University, Chongqing, People's Republic of China.

Department of Nephrology, Southwest Hospital, Army Medical University, Chongqing, People's Republic of China.

出版信息

J Inflamm Res. 2023 Oct 13;16:4503-4526. doi: 10.2147/JIR.S418222. eCollection 2023.

DOI:10.2147/JIR.S418222
PMID:37854313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10581022/
Abstract

Hyperoside is a flavonol glycoside mainly found in plants of the genera and , and also detected in many plant species such as , , , , and . This compound exhibits a multitude of biological functions including anti-inflammatory, antidepressant, antioxidative, vascular protective effects and neuroprotective effects, etc. This review summarizes the quantification, original plant, chemical structure and property, structure-activity relationship, pharmacologic effect, pharmacokinetics, toxicity and clinical application of hyperoside, which will be significant for the exploitation for new drug and full utilization of this compound.

摘要

金丝桃苷是一种黄酮醇苷，主要存在于[此处原文未给出具体属名]属植物中，在许多植物物种如[此处原文未给出具体植物名]、[此处原文未给出具体植物名]、[此处原文未给出具体植物名]、[此处原文未给出具体植物名]、[此处原文未给出具体植物名]和[此处原文未给出具体植物名]中也有检测到。该化合物具有多种生物学功能，包括抗炎、抗抑郁、抗氧化、血管保护作用和神经保护作用等。本综述总结了金丝桃苷的定量分析、原始植物、化学结构与性质、构效关系、药理作用、药代动力学、毒性及临床应用，这对于该化合物的新药开发和充分利用具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/450abdfde014/JIR-16-4503-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/84f4538b5c4f/JIR-16-4503-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/6ee3d3b06e08/JIR-16-4503-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/450548b836ae/JIR-16-4503-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/450abdfde014/JIR-16-4503-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/84f4538b5c4f/JIR-16-4503-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/6ee3d3b06e08/JIR-16-4503-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/450548b836ae/JIR-16-4503-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbd0/10581022/450abdfde014/JIR-16-4503-g0004.jpg

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