多发性硬化症（MS）患者中炎症性肠病（IBD）的患病率：一项系统评价和荟萃分析。
The Prevalence of Inflammatory Bowel Disease (IBD) in Patients with Multiple Sclerosis (MS): A Systematic Review and Meta-Analysis.
作者信息
Nasirzadeh Amirreza, Jahanshahi Reza, Ghajarzadeh Mahsa, Mohammadi Aida, Moghadasi Abdorreza Naser
机构信息
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Neurology, University of Medical Sciences, Gorgan, Iran.
出版信息
Int J Prev Med. 2023 Jun 22;14:81. doi: 10.4103/ijpvm.ijpvm_44_22. eCollection 2023.
BACKGROUND
This systematic review and meta-analysis aim to update the pooled prevalence of Inflammatory bowel disease (IBD) in patients with multiple sclerosis (MS).
METHODS
Two researchers independently and systematically searched PubMed, Scopus, EMBASE, Web of Science, and google scholar. They also searched for references of the included studies, and conference abstracts that were published up to September 2021.
RESULTS
The literature search revealed 5719 articles, after deleting duplicates 3616 remained. Finally, 17 studies were included. The pooled prevalence of IBD in MS was 1% (I = 96.3%, < 0.001). The pooled odds ratio of developing IBD in MS cases was 1.36 (95% CI: 1.1-1.6) (I = 58.3, = 0.01).
CONCLUSIONS
The results of this systematic review and meta-analysis show that the pooled prevalence of IBD in MS patients was 1% and the pooled odds ratio of developing IBD in MS cases was 1.36.
背景
本系统评价和荟萃分析旨在更新多发性硬化症（MS）患者中炎症性肠病（IBD）的合并患病率。
方法
两名研究人员独立且系统地检索了PubMed、Scopus、EMBASE、Web of Science和谷歌学术。他们还检索了纳入研究的参考文献以及截至2021年9月发表的会议摘要。
结果
文献检索共找到5719篇文章，删除重复项后剩余3616篇。最终纳入17项研究。MS患者中IBD的合并患病率为1%（I = 96.3%，P < 0.001）。MS患者发生IBD的合并比值比为1.36（95%CI：1.1 - 1.6）（I = 58.3，P = 0.01）。
结论
本系统评价和荟萃分析结果表明，MS患者中IBD的合并患病率为1%，MS患者发生IBD的合并比值比为1.36。
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