Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.
Nucleic Acids Res. 2024 Jan 5;52(D1):D1677-D1682. doi: 10.1093/nar/gkad896.
LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org, provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS provides databases for cataloging and identifying lipids at varying levels of characterization in addition to numerous software tools and educational resources, and became an ELIXIR-UK data resource in 2020. This paper describes the expansion of existing databases in LIPID MAPS, including richer metadata with literature provenance, taxonomic data and improved interoperability to facilitate FAIR compliance. A joint project funded by ELIXIR-UK, in collaboration with WikiPathways, curates and hosts pathway data, and annotates lipids in the context of their biochemical pathways. Updated features of the search infrastructure are described along with implementation of programmatic access via API and SPARQL. New lipid-specific databases have been developed and provision of lipidomics tools to the community has been updated. Training and engagement have been expanded with webinars, podcasts and an online training school.
脂质图谱（脂质代谢物和途径策略），www.lipidmaps.org，提供了一种系统和标准化的方法来组织脂质结构和生化数据。该组织成立于 20 年前，其脂质图谱命名法和分类已成为公认的行业标准。脂质图谱提供了数据库，用于对不同特征水平的脂质进行编目和识别，此外还有许多软件工具和教育资源，并于 2020 年成为了 ELIXIR-UK 的一个数据资源。本文介绍了脂质图谱中现有数据库的扩展，包括更丰富的元数据，包括文献来源、分类学数据以及改进的互操作性，以促进 FAIR 合规性。一个由 ELIXIR-UK 资助的联合项目与 WikiPathways 合作，对途径数据进行编目和托管，并在其生化途径的背景下注释脂质。本文描述了搜索基础设施的更新功能，以及通过 API 和 SPARQL 实现的编程访问。新的脂质专用数据库已经开发完成，向社区提供的脂质组学工具也得到了更新。培训和参与也得到了扩展，包括网络研讨会、播客和在线培训学校。
