Institute of Veterinary Sciences, University of Saad Dahlab Blida, Blida, Algeria.
Department of Veterinary Sciences, University of Messina, Messina, Italy.
Microb Drug Resist. 2023 Dec;29(12):576-581. doi: 10.1089/mdr.2022.0165. Epub 2023 Oct 19.
The current study aimed to determine the occurrence and antimicrobial resistance of oral in stray dogs and cats in Algeria. Oral swabs from 200 stray animals (100 dogs and 100 cats) were collected and cultured on Columbia agar medium supplemented with 5% defibrinated sheep blood. Isolates were identified using analytical profile index Rapid 20 Strep commercial kits, and antibiotic susceptibility was determined using the disk diffusion method. Of the 200 animals sampled, 34 carried in their oral cavities, with 26 isolates (76.47%) resistant to at least 2 drugs. Multidrug resistance profiles (to more than three different antimicrobials) were observed only in cats (26.08% of isolates). More isolates were resistant to erythromycin and tetracycline (71% and 65%, respectively) than to other antimicrobials. This is the first research study in Algeria detecting antimicrobial resistance in oral isolated from dogs and cats and highlights potential public health concerns. Clinical trials registration number: 01/2018.
本研究旨在确定阿尔及利亚流浪犬和猫口腔 的发生情况及其对抗菌药物的耐药性。采集 200 只流浪动物（100 只狗和 100 只猫）的口腔拭子，接种于哥伦比亚琼脂培养基中，该培养基中添加了 5%的脱纤维绵羊血。采用分析性能指数快速 20 链球菌商业试剂盒对分离株进行鉴定，并采用纸片扩散法测定抗生素敏感性。在 200 只采样动物中，有 34 只动物口腔中携带 ，其中 26 株（76.47%）对至少 2 种药物耐药。仅在猫（26.08%的分离株）中观察到多药耐药（对超过三种不同抗菌药物耐药）。与其他抗菌药物相比，更多的分离株对红霉素和四环素（分别为 71%和 65%）耐药。这是阿尔及利亚首次在犬和猫口腔分离的 中检测到抗菌药物耐药性的研究，提示了潜在的公共卫生问题。临床试验注册号：01/2018。
