Kataoka Yasushi, Umino Yurie, Ochi Hiroki, Harada Kazuki, Sawada Takuo
Department of Veterinary Microbiology, Nippon Veterinary and Life Science University, Tokyo 180-8602, Japan.
J Vet Med Sci. 2014 Oct;76(10):1399-402. doi: 10.1292/jvms.13-0576. Epub 2014 Jun 30.
In this study, we examined the antimicrobial susceptibility of the enterococci isolated from dogs and cats in Japan during 2011-2012. Fecal samples were collected from 84 dogs and 16 cats that underwent antibiotic treatment. Enterococci were detected in 70 of 84 dogs (83.3%) and 7 of 16 cats (43.8%). The most prevalent Enterococcus species was Enterococcus faecalis (64.9%); Enterococcus faecium and Enterococcus durans were also isolated from 14 of 77 (18.2%) and 5 of 77 (6.5%) of these animals, respectively. The most active resistance was observed for erythromycin (44.2%) and oxytetracycline (44.2%), and there was considerable resistance to lincomycin (41.6%), gentamicin (31.2%) and kanamycin (31.2%). Compared with the results of a similar study conducted in 2006 and 2007, enterococci susceptibility to enrofloxacin and ampicillin had significantly increased. Enterococcus gallinarum harboring vanC1 and Enterococcus casseliflavus harboring vanC2/3 were isolated from 4 of 77 enterococcal isolates. However, no enterococcal isolates were resistant to vancomycin. Multidrug resistance was found for as few as two and as many as nine antimicrobials regardless of the class. These results demonstrate that dogs and cats treated with antibiotics are commonly colonized with antimicrobial-resistant enterococci.
在本研究中，我们检测了2011 - 2012年期间从日本犬猫分离出的肠球菌的抗菌药敏性。从84只犬和16只接受抗生素治疗的猫采集粪便样本。在84只犬中有70只（83.3%）检测到肠球菌，16只猫中有7只（43.8%）检测到肠球菌。最常见的肠球菌种类是粪肠球菌（64.9%）；屎肠球菌和耐久肠球菌也分别从这些动物中的77只里的14只（18.2%）和77只里的5只（6.5%）中分离得到。观察到对红霉素（44.2%）和土霉素（44.2%）的耐药性最强，对林可霉素（41.6%）、庆大霉素（31.2%）和卡那霉素（31.2%）有相当程度的耐药性。与2006年和2007年进行的类似研究结果相比，肠球菌对恩诺沙星和氨苄西林的敏感性显著增加。从77株肠球菌分离物中有4株分离出携带vanC1的鹑鸡肠球菌和携带vanC2/3的格氏肠球菌。然而，没有肠球菌分离物对万古霉素耐药。无论抗菌药物类别如何，发现对少至两种多达九种抗菌药物存在多重耐药性。这些结果表明，接受抗生素治疗的犬猫通常被耐药性肠球菌定植。
