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研发具有生物活性的涂层牙线:抗菌和机械性能评估。

Developing a bioactive glass coated dental floss: antibacterial and mechanical evaluations.

机构信息

Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, 91058, Erlangen, Germany.

Departamento de Ingeniería y Ciencia de los Materiales y del Transporte, Escuela Politécnica Superior, Universidad de Sevilla, 41011, Seville, Spain.

出版信息

J Mater Sci Mater Med. 2023 Oct 19;34(11):53. doi: 10.1007/s10856-023-06758-8.

DOI:10.1007/s10856-023-06758-8
PMID:37855952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10587244/
Abstract

In the present study, we investigated commercial dental floss coated with chitosan or chitosan + mesoporous bioactive glass nanoparticles (MBGNs) in order to determine the antimicrobial and mechanical properties of the newly fabricated flosses. Whereas these coatings showed notable ability to inhibit growth of both Gram (+) and Gram (-) bacteria after 24 h, the impact was negligible at 3 h. Furthermore, the tensile strength of the floss was improved by the addition of these layers, making it more durable and effective for cleaning between teeth. We therefore propose enhanced investigations of these composites since they demonstrate enormous potential in promoting oral health.

摘要

在本研究中,我们研究了涂有壳聚糖或壳聚糖+介孔生物活性玻璃纳米颗粒(MBGNs)的商业牙线,以确定新制造的牙线的抗菌和机械性能。虽然这些涂层在 24 小时后显示出显著抑制革兰氏阳性和革兰氏阴性细菌生长的能力,但在 3 小时时影响可以忽略不计。此外,通过添加这些层可以提高牙线的拉伸强度,使其在清洁牙齿之间更耐用和有效。因此,我们建议对这些复合材料进行进一步研究,因为它们在促进口腔健康方面具有巨大的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/02342dd88943/10856_2023_6758_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/cdff36c32e0c/10856_2023_6758_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/e6088acb90aa/10856_2023_6758_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/cff498065353/10856_2023_6758_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/a54a00ffed74/10856_2023_6758_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/ee1f2ab749df/10856_2023_6758_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/afc343bc4903/10856_2023_6758_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/02342dd88943/10856_2023_6758_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/cdff36c32e0c/10856_2023_6758_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/e6088acb90aa/10856_2023_6758_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/cff498065353/10856_2023_6758_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/a54a00ffed74/10856_2023_6758_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/ee1f2ab749df/10856_2023_6758_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/afc343bc4903/10856_2023_6758_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed4/10587244/02342dd88943/10856_2023_6758_Fig7_HTML.jpg

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本文引用的文献

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Front Bioeng Biotechnol. 2023 Apr 3;11:1065597. doi: 10.3389/fbioe.2023.1065597. eCollection 2023.
2
Drug-Coated Floss to Treat Gum Diseases: In Vitro and In Vivo Characterization.药物涂层牙线治疗牙龈疾病:体外和体内特性研究。
ACS Appl Mater Interfaces. 2022 Jun 29;14(25):28663-28670. doi: 10.1021/acsami.2c07976. Epub 2022 Jun 15.
3
Sol-gel bioactive glass containing biomaterials for restorative dentistry: A review.
用于口腔修复学的含溶胶-凝胶生物活性玻璃的生物材料:综述
Dent Mater. 2022 May;38(5):725-747. doi: 10.1016/j.dental.2022.02.011. Epub 2022 Mar 14.
4
Performance Evaluation of Dental Flosses Pre- and Post-Utilization.牙线使用前后的性能评估
Materials (Basel). 2022 Feb 18;15(4):1522. doi: 10.3390/ma15041522.
5
Coated floss for drug delivery into the gum pocket.用于将药物递送至牙周袋的涂层牙线。
Int J Pharm. 2021 Sep 5;606:120855. doi: 10.1016/j.ijpharm.2021.120855. Epub 2021 Jul 2.
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Functionalized Mouth-Conformable Interfaces for pH Evaluation of the Oral Cavity.用于口腔 pH 值评估的功能化口腔顺应性界面。
Adv Sci (Weinh). 2021 Jun;8(12):e2003416. doi: 10.1002/advs.202003416. Epub 2021 Mar 18.
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Novel nanosystems to enhance biological activity of hydroxyapatite against dental caries.新型纳米系统增强羟基磷灰石对龋齿的生物活性。
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