Battistini F, Cordero C, Urcuyo F G, Rojas R F, Ollague W, Zaias N
Int J Dermatol. 1983 Jul-Aug;22(6):388-9. doi: 10.1111/j.1365-4362.1983.tb01215.x.
In a double-blind study, the efficacy of 1% tolnaftate cream, 3% undecylenic acid and its zinc salt, and a placebo cream were tested in dermatophytosis of the glaborous skin and groin. Ninety-seven subjects completed the study: 33 received tolnaftate, 23 of these subjects were cured clinically and mycologically. Thirty-two subjects received 3% undecylenic acid and 20% zinc undecylenate as a cream. Of these, 21 were cured clinically and mycologically. Only three of the 32 subjects receiving placebo were cured clinically and mycologically. Both tolnaftate and undecylenic acid and its zinc salt are effective in this condition.
在一项双盲研究中，对1%托萘酯乳膏、3%十一烯酸及其锌盐乳膏和一种安慰剂乳膏治疗光滑皮肤和腹股沟皮肤癣菌病的疗效进行了测试。97名受试者完成了该研究：33人接受托萘酯治疗，其中23人临床和真菌学治愈。32名受试者接受了含3%十一烯酸和20%十一烯酸锌的乳膏治疗。其中，21人临床和真菌学治愈。接受安慰剂治疗的32名受试者中只有3人临床和真菌学治愈。托萘酯和十一烯酸及其锌盐在这种情况下均有效。
