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与双膦酸盐治疗相关的非典型股骨干骨折中股管闭塞的罕见病例。

A Rare Case of Obliterated Femoral Canal in Atypical Femoral Shaft Fracture Related to Bisphosphonate Therapy.

作者信息

Febrian Kunta Adjie Riko, Bajuri Mohd Yazid, Nik Abdullah Nik Alif, Leong Juzaily F

机构信息

Orthopaedics and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.

出版信息

Cureus. 2023 Sep 18;15(9):e45441. doi: 10.7759/cureus.45441. eCollection 2023 Sep.

Abstract

Bisphosphonates have been accepted as the first-line treatment for postmenopausal osteoporosis. Atypical femoral shaft fracture is one of the side effects of long-term bisphosphonate therapy. The mainstay treatment of this atypical fracture is bisphosphonates cessation and stabilization with internal fixation. We are reporting a rare case of a blocked intramedullary femoral canal found during surgery of an 85-year-old Indian lady with an atypical femoral shaft fracture related to her five-year alendronate therapy. We found difficulty in passing the guidewire through the fracture site during the closed method, which renders open reduction to manage the obliterated intramedullary canal. The importance of changing decisions intraoperatively should be highlighted to avoid further complications. Fracture union is achieved during our follow-up in the clinic.

摘要

双膦酸盐已被公认为绝经后骨质疏松症的一线治疗药物。非典型股骨干骨折是长期双膦酸盐治疗的副作用之一。这种非典型骨折的主要治疗方法是停用双膦酸盐并通过内固定进行稳定。我们报告了一例罕见病例,在一名85岁印度女性因非典型股骨干骨折接受手术时,发现其股骨髓内管堵塞,该骨折与她五年的阿仑膦酸钠治疗有关。我们发现在闭合复位方法中,导丝难以穿过骨折部位,这使得需要切开复位来处理闭塞的髓内管。应强调术中改变决策的重要性,以避免进一步的并发症。在我们的临床随访中实现了骨折愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed2b/10583126/d73eff80fd78/cureus-0015-00000045441-i01.jpg

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