视前区热敏神经元对致变温肽——蛙皮素和神经降压素的反应。
Responses of preoptic thermosensitive neurons to poikilothermia-inducing peptides--bombesin and neurotensin.
作者信息
Hori T, Yamasaki M, Kiyohara T, Shibata M
出版信息
Pflugers Arch. 1986 Nov;407(5):558-60. doi: 10.1007/BF00657516.
PMID:3786114
Abstract
Microelectrophoretic application of bombesin (BS) and neurotensin (NT) to thermosensitive and non-thermosensitive neurons in the preoptic and anterior hypothalamus (PO/AH) of anesthetized rats depressed the activity of 78 (54.2%) of 144 neurons and that of 66 (51.6%) of 128 neurons, respectively. The depressing effects of both peptides which were uniformly observed across warm-sensitive and cold-sensitive neurons in the PO/AH are consistent with their poikilothermic actions.
摘要
向麻醉大鼠视前区和下丘脑前部（PO/AH）的热敏和非热敏神经元微量电泳应用蛙皮素（BS）和神经降压素（NT），分别使144个神经元中的78个（54.2%）和128个神经元中的66个（51.6%）的活动受到抑制。在PO/AH中，这两种肽对温敏和冷敏神经元均产生一致的抑制作用，这与其变温动物作用相符。
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