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视前区热敏神经元对致变温肽——蛙皮素和神经降压素的反应。

Responses of preoptic thermosensitive neurons to poikilothermia-inducing peptides--bombesin and neurotensin.

作者信息

Hori T, Yamasaki M, Kiyohara T, Shibata M

出版信息

Pflugers Arch. 1986 Nov;407(5):558-60. doi: 10.1007/BF00657516.

DOI:10.1007/BF00657516
PMID:3786114
Abstract

Microelectrophoretic application of bombesin (BS) and neurotensin (NT) to thermosensitive and non-thermosensitive neurons in the preoptic and anterior hypothalamus (PO/AH) of anesthetized rats depressed the activity of 78 (54.2%) of 144 neurons and that of 66 (51.6%) of 128 neurons, respectively. The depressing effects of both peptides which were uniformly observed across warm-sensitive and cold-sensitive neurons in the PO/AH are consistent with their poikilothermic actions.

摘要

向麻醉大鼠视前区和下丘脑前部(PO/AH)的热敏和非热敏神经元微量电泳应用蛙皮素(BS)和神经降压素(NT),分别使144个神经元中的78个(54.2%)和128个神经元中的66个(51.6%)的活动受到抑制。在PO/AH中,这两种肽对温敏和冷敏神经元均产生一致的抑制作用,这与其变温动物作用相符。

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Responses of preoptic thermosensitive neurons to poikilothermia-inducing peptides--bombesin and neurotensin.视前区热敏神经元对致变温肽——蛙皮素和神经降压素的反应。
Pflugers Arch. 1986 Nov;407(5):558-60. doi: 10.1007/BF00657516.
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本文引用的文献

1
The effects of bombesin injected into The anterior and posterior hypothalamus on body temperature and oxygen consumption.注射到下丘脑前部和后部的蛙皮素对体温和耗氧量的影响。
Neuropharmacology. 1980 Nov;19(11):1095-7. doi: 10.1016/0028-3908(80)90107-0.
2
Bombesin-induced poikilothermy in rats.蛙皮素诱导大鼠体温随环境温度变化。
Brain Res. 1980 Apr 28;188(2):525-30. doi: 10.1016/0006-8993(80)90050-5.
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Bombesin acts in preoptic area to produce hypothermia in rats.
Life Sci. 1980 Mar 3;26(9):725-30. doi: 10.1016/0024-3205(80)90262-3.
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Hypothermia elicited by the intracerebral microinjection of neurotensin.脑室内微量注射神经降压素引起的体温过低。
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Neuronal location of the bombesin-like immunoreactivity in the central nervous system of the rat.大鼠中枢神经系统中蛙皮素样免疫反应性的神经元定位。
Regul Pept. 1982 Oct;4(5):275-83. doi: 10.1016/0167-0115(82)90120-3.
6
Neurotensin: topographical distribution of brain sites involved in hypothermia and antinociception.神经降压素:参与体温过低和抗伤害感受的脑区的拓扑分布。
J Comp Neurol. 1982 Sep 20;210(3):225-38. doi: 10.1002/cne.902100303.
7
Responses of preoptic thermosensitive neurons to medial forebrain bundle stimulation.视前区热敏神经元对内侧前脑束刺激的反应。
Brain Res Bull. 1982 Jun;8(6):667-75. doi: 10.1016/0361-9230(82)90094-6.
8
Analysis of the thermolytic action of ICV neurotensin in the rat at different ambient temperatures.不同环境温度下大鼠脑室内神经降压素的热分解作用分析。
Brain Res Bull. 1983 May;10(5):661-5. doi: 10.1016/0361-9230(83)90035-7.
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Changes in body temperature and thermosensitivity of preoptic and septal neurons during hippocampal stimulation.
Brain Res Bull. 1984 Jul;13(1):93-8. doi: 10.1016/0361-9230(84)90011-x.
10
Effects of intraventricular administration of neurotensin and somatostatin on thermoregulation in the rat.脑室内注射神经降压素和生长抑素对大鼠体温调节的影响。
Neuropharmacology. 1981 Jul;20(7):715-8. doi: 10.1016/0028-3908(81)90122-2.