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精神分裂症成人的数字化表型:叙事综述。

Digital Phenotyping in Adults with Schizophrenia: A Narrative Review.

机构信息

Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02115, USA.

Slaight Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, ON, Canada.

出版信息

Curr Psychiatry Rep. 2023 Nov;25(11):699-706. doi: 10.1007/s11920-023-01467-z. Epub 2023 Oct 20.

DOI:10.1007/s11920-023-01467-z
PMID:37861979
Abstract

PURPOSE OF REVIEW

As care for older adult patients with schizophrenia lacks innovation, technology can help advance the field. Specifically, digital phenotyping, the real-time monitoring of patients' behaviors through smartphone sensors and symptoms through surveys, holds promise as the method can capture the dynamicity and environmental correlates of disease.

RECENT FINDINGS

Few studies have used digital phenotyping to elucidate adult patients' experiences with schizophrenia. In this narrative review, we summarized the literature using digital phenotyping on adults with schizophrenia. No study focused solely on older adult patients. Studies including all adult patients were heterogeneous in measures used, duration, and outcomes. Despite limited research, digital phenotyping shows potential for monitoring outcomes such as negative, positive, and functional symptoms, as well as predicting relapse. Future research should work to target the symptomology persistent in chronic schizophrenia and ensure all patients have the digital literacy required to benefit from digital interventions and homogenize datasets to allow for more robust conclusions.

摘要

目的综述

由于对老年精神分裂症患者的护理缺乏创新,因此技术可以帮助该领域取得进展。具体而言,通过智能手机传感器实时监测患者行为以及通过调查监测症状的数字表型,有望成为一种可以捕捉疾病动态和环境相关性的方法。

最新发现

很少有研究使用数字表型来阐明成年精神分裂症患者的体验。在这篇叙述性综述中,我们总结了使用数字表型对成年精神分裂症患者进行研究的文献。没有研究专门针对老年患者。包括所有成年患者的研究在使用的措施、持续时间和结果方面存在差异。尽管研究有限,但数字表型在监测阴性、阳性和功能症状等结果方面显示出潜力,并且可以预测复发。未来的研究应致力于针对慢性精神分裂症中持续存在的症状,并确保所有患者都具备数字素养,从而受益于数字干预措施,并使数据集同质化,以得出更可靠的结论。

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Schizophrenia (Heidelb). 2023 Jan 27;9(1):6. doi: 10.1038/s41537-023-00332-5.
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Digital Phenotyping for Differential Diagnosis of Major Depressive Episode: Narrative Review.用于重度抑郁发作鉴别诊断的数字表型分析:叙述性综述
JMIR Ment Health. 2023 Jan 23;10:e37225. doi: 10.2196/37225.
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Socioeconomic burden of schizophrenia: a targeted literature review of types of costs and associated drivers across 10 countries.
早期精神病服务使用者对数字远程监测的看法:一项定性研究。
BMC Psychiatry. 2025 Apr 16;25(1):386. doi: 10.1186/s12888-025-06859-4.
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Utilizing Technology to Enhance the Ecological Validity of Cognitive and Functional Assessments in Schizophrenia: An Overview of the State-of-the-Art.利用技术提高精神分裂症认知和功能评估的生态效度:最新进展综述
Schizophr Bull Open. 2024 Nov 28;5(1):sgae025. doi: 10.1093/schizbullopen/sgae025. eCollection 2024 Jan.
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JMIR Hum Factors. 2024 Nov 22;11:e59974. doi: 10.2196/59974.
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