Department of Endocrinology and Metabolism, Affiliated Hospital of Weifang Medical University, Weifang, China.
Department of Clinical Research Center, Affiliated Hospital of Weifang Medical University, Weifang, China.
BMJ Open. 2023 Oct 21;13(10):e075437. doi: 10.1136/bmjopen-2023-075437.
To analyse the trends of diseases burden attributed to high body mass index (BMI), including overweight and obesity, in Asia from 1990 to 2019.
Observational study.
The data of 45 countries and regions in Asia were obtained from the Global Burden of Disease Study 2019 database.
Numbers, age-standardised rate (ASR) of deaths and disability-adjusted life years (DALYs), and the corresponding estimated annual percentage changes (EAPCs), attributable to high BMI in Asia from 1990 to 2019, were analysed by regions, genders and age. We also analysed changes in the causes of deaths and DALYs that are attributable to high BMI over this period.
In 2019, all causes deaths attributable to high BMI in Asia were 2 329 503, with increases by 265% compared with 1990. Over three decades, DALYs related to high BMI have increased by 268%. The ASRs of deaths and DALYs in Asia both showed continuous upward trends during this period (EAPC 1.39; 95% certainty interval [95% CI] 1.35 to 1.43 for deaths; EAPC 1.8; 95% CI 1.76 to 1.84 for DALYs), while both were declined in high-income areas (EAPC -2.03 and -1.26). By geographical regions, disease burden in Central Asia and West Asia have been fluctuating at high levels, but high-income Asia Pacific showed decreasing trends of ASR of deaths (EAPC -2.03) and DALYs (EAPC -1.26). Over this period, disease burden in Asia was changing from women to men, and tends to ageing. In addition, diabetes were the diseases most affected by high BMI, and cancer burden was high in middle-aged and elderly people.
The disease burden attributed to high BMI in Asia has experienced great changes. It is necessary to promote the prevention of obesity and chronic diseases in a comprehensive manner, especially in low-income areas, men and elderly.
分析 1990 年至 2019 年亚洲地区因高体重指数（BMI）导致的疾病负担趋势，包括超重和肥胖。
观察性研究。
亚洲 45 个国家和地区的数据来自 2019 年全球疾病负担研究数据库。
按地区、性别和年龄分析 1990 年至 2019 年亚洲地区因高 BMI 导致的死亡人数、年龄标准化率（ASR）、伤残调整生命年（DALY）以及相应的估计年百分比变化（EAPC）；分析这一时期高 BMI 导致的死亡和 DALY 原因的变化。
2019 年，亚洲因高 BMI 导致的所有死因死亡人数为 2329503 例，比 1990 年增加了 265%。三十年来，与高 BMI 相关的 DALY 增加了 268%。在此期间，亚洲的死亡率和 DALY 的 ASR 均呈持续上升趋势（死亡率的 EAPC 为 1.39；95%置信区间[95%CI]为 1.35 至 1.43；DALY 的 EAPC 为 1.8；95%CI 为 1.76 至 1.84），而高收入地区的死亡率和 DALY 呈下降趋势（EAPC 分别为-2.03 和-1.26）。按地理位置划分，中亚和西亚的疾病负担一直在高水平波动，而高收入亚太地区的死亡率 ASR（EAPC-2.03）和 DALY（EAPC-1.26）呈下降趋势。在此期间，亚洲的疾病负担从女性向男性转移，且有老龄化趋势。此外，糖尿病是受高 BMI 影响最大的疾病，癌症负担在中老年人中较高。
亚洲因高 BMI 导致的疾病负担发生了重大变化。有必要全面促进肥胖和慢性病的预防，特别是在低收入地区、男性和老年人中。
