Central Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, China.
Departments of Public Health and Preventive Medicine, Jinan University, Guangzhou, China.
BMC Public Health. 2023 Nov 14;23(1):2242. doi: 10.1186/s12889-023-17162-w.
Low physical activity (LPA) is linked to the risk of stroke, but the disease burden of stroke attributable to LPA needs to be understood to develop effective preventive strategies. We aim to assess spatiotemporal trends in the global burden of stroke attributable to LPA from 1990 to 2019.
Based on the Global Burden of Disease, Injuries, and Risk Factors Study, our research examined deaths, the Disability-Adjusted Life Years (DALYs), the Age-Standardized Mortality Rate (ASMR), the Age-Standardized DALY Rate (ASDR), and the Estimated Annual Percentage Change (EAPC) for stroke attributable to LPA.
Deaths and DALYs were on the rise worldwide from 1990 to 2019, with increases of 72.72% for the former and 67.41% for the latter; ASMR and ASDR decreased, with the ASMR-related EAPC of -1.61 (95% CI:-1.71--1.5) and ASDR-related EAPC of -1.35 (95% CI:-1.43--1.27); females had more numbers of deaths and DALYs, and the majorities of deaths and DALYs were shared by those aged ≥ 70. The highest burden rates were shared by North Africa, the Middle East, and Tropical Latin America; the ASMR-related EAPC was associated with the ASMR in 1990 (R = -0.26, P < 0.001) and the Socio-Demographic Index (SDI) across different countries in 2019 (R = -0.61, P < 0.001), respectively, and such patterns were similar to what ASDR and the ASDR-related EAPC had; the Human Development Index (HDI) in 2019 was associated with the ASMR-related EAPC (R = 0.63, P < 0.001) and the ASDR-related EAPC across different countries (R = -0.62, P < 0.001), respectively.
Globally, deaths and DALYs of stroke attributable to LPA were on the rise, although their age-standardized rates presented downward over the past three decades; the burden of stroke attributable to LPA showed upward trends especially in those aged ≥ 70 and females in the regions of East Asia, North Africa, and the Middle East, which need more attention to the effects of physical activity on health interventions.
低身体活动（LPA）与中风风险有关，但需要了解与 LPA 相关的中风疾病负担，以制定有效的预防策略。本研究旨在评估 1990 年至 2019 年全球与 LPA 相关的中风负担的时空趋势。
基于全球疾病、伤害和危险因素研究，我们研究了与 LPA 相关的中风导致的死亡、残疾调整生命年（DALYs）、年龄标准化死亡率（ASMR）、年龄标准化 DALY 率（ASDR）和估计年百分比变化（EAPC）。
1990 年至 2019 年，全球范围内与 LPA 相关的中风死亡人数和 DALYs 呈上升趋势，前者增加了 72.72%，后者增加了 67.41%；ASMR 和 ASDR 下降，ASMR 相关的 EAPC 为-1.61（95%CI：-1.71-1.5），ASDR 相关的 EAPC 为-1.35（95%CI：-1.43-1.27）；女性的死亡人数和 DALYs 更多，70 岁及以上人群的死亡人数和 DALYs 占大多数。北非、中东和热带拉丁美洲的负担率最高；ASMR 相关的 EAPC 与 1990 年的 ASMR（R=-0.26，P<0.001）和 2019 年不同国家的社会人口指数（SDI）相关（R=-0.61，P<0.001），这些模式与 ASDR 和 ASDR 相关的 EAPC 相似；2019 年人类发展指数（HDI）与 ASMR 相关的 EAPC（R=0.63，P<0.001）和不同国家的 ASDR 相关的 EAPC 相关（R=-0.62，P<0.001）。
全球范围内，与 LPA 相关的中风死亡人数和 DALYs 呈上升趋势，尽管过去三十年其年龄标准化率呈下降趋势；与 LPA 相关的中风负担呈上升趋势，尤其是在东亚、北非和中东地区年龄在 70 岁及以上和女性中，这些地区需要更加关注身体活动对健康干预的影响。
