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荷尔蒙不公:环境毒素是内分泌健康差异的驱动因素。

Hormonal Injustice: Environmental Toxicants as Drivers of Endocrine Health Disparities.

机构信息

School of Public Health, University of Illinois at Chicago, 1603 West Taylor Street, Chicago, IL 60612, USA; College of Medicine, University of Illinois at Chicago, 1853 West Polk Street, Chicago, IL 60612, USA; Division of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago, 835 South Wolcott, Suite E625, M/C 640, Chicago, IL 60612, USA.

College of Medicine, University of Illinois at Chicago, 1853 West Polk Street, Chicago, IL 60612, USA; Division of Endocrinology, Diabetes, and Metabolism, University of Illinois at Chicago, 835 South Wolcott, Suite E625, M/C 640, Chicago, IL 60612, USA.

出版信息

Endocrinol Metab Clin North Am. 2023 Dec;52(4):719-736. doi: 10.1016/j.ecl.2023.05.009. Epub 2023 Jun 11.

Abstract

The toll of multiple endocrine disorders has increased substantially in recent decades, and marginalized populations bear a disproportionate burden of disease. Because of the significant individual and societal impact of these conditions, it is essential to identify and address all modifiable risk factors contributing to these disparities. Abundant evidence now links endocrine dysfunction with exposure to endocrine-disrupting chemicals (EDCs), with greater exposures to multiple EDCs occurring among vulnerable groups, such as racial/ethnic minorities, those with low incomes, and others with high endocrine disease burdens. Identifying and eliminating EDC exposures is an essential step in achieving endocrine health equity.

摘要

近年来,多种内分泌疾病的发病率显著上升,边缘化人群承受着不成比例的疾病负担。由于这些疾病对个人和社会的重大影响,因此必须确定并解决导致这些差异的所有可改变的风险因素。大量证据表明,内分泌功能障碍与接触内分泌干扰化学物质(EDCs)有关,弱势群体(如少数族裔、低收入人群和其他内分泌疾病负担较高的人群)接触多种 EDC 的情况更为严重。识别和消除 EDC 暴露是实现内分泌健康公平的重要步骤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14a1/10929240/b1d9b644a46d/nihms-1970648-f0001.jpg

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