Pu Lutong, Li Jialin, Qi Weitang, Zhang Jinquan, Chen Hongyu, Tang Zihuan, Han Yuchi, Wang Jie, Chen Yucheng
Department of Cardiology, West China Hospital, Sichuan University, Sichuan Province, Guoxue Xiang No. 37, Chengdu, 610041, China.
West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.
Heart Fail Rev. 2024 Mar;29(2):395-404. doi: 10.1007/s10741-023-10355-w. Epub 2023 Oct 22.
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder characterized by left ventricular hypertrophy. Sudden cardiac death (SCD) is a rare but the most catastrophic complication in patients with HCM. Implantable cardioverter-defibrillators (ICDs) are widely recognized as effective preventive measures for SCD. Individualized risk stratification and early intervention in HCM can significantly improve patient prognosis. In this study, we review the latest findings regarding pathogenesis, risk stratification, and prevention of SCD in HCM patients, highlighting the clinic practice of cardiovascular magnetic resonance imaging for SCD management.
肥厚型心肌病（HCM）是一种常染色体显性疾病，其特征为左心室肥厚。心脏性猝死（SCD）是HCM患者中一种罕见但最具灾难性的并发症。植入式心脏复律除颤器（ICD）被广泛认为是预防SCD的有效措施。对HCM进行个体化风险分层和早期干预可显著改善患者预后。在本研究中，我们回顾了有关HCM患者SCD发病机制、风险分层及预防的最新研究结果，重点介绍了心血管磁共振成像在SCD管理中的临床应用。
