从益智果实中分离得到的两种新倍半萜类化合物。
Two new sesquiterpenoids from the fruits of Alpinia oxyphylla.
作者信息
Bai Weirong, Wang Tuanjie, Yang Xiaoming, Wang Zhenzhong, Li Haibo, Geng Jianliang
机构信息
College of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Jiangsu Kanion Pharmaceutical Co. Ltd, Lianyungang, Jiangsu, China.
出版信息
Nat Prod Res. 2025 Feb;39(3):468-474. doi: 10.1080/14786419.2023.2272282. Epub 2023 Oct 22.
Two undescribed sesquiterpenoids, including one nor-eudesmane type () and one guaiane type (), together with two known analogues (-) have been isolated and identified from the fruits of . The structures of these new compounds were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, HRESIMS, IR, UV) and NMR calculations with DP4+ analysis. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE production in LPS stimulated RAW 264.7 macrophages.
从[植物名称]果实中分离并鉴定出两种未描述的倍半萜类化合物，包括一种降桉烷型（）和一种愈创木烷型（），以及两种已知类似物（-）。通过广泛的光谱分析（1D-、2D-NMR、HRESIMS、IR、UV）和使用DP4 +分析的NMR计算阐明了这些新化合物的结构。通过测量所有分离物对脂多糖刺激的RAW 264.7巨噬细胞中PGE产生的抑制作用来评估其抗炎活性。
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