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[肝衰竭患者非生物型人工肝支持系统治疗的研究进展]

[Research progress of non-biological artificial liver support system therapy for paitents with liver failure].

作者信息

Ma Y J, Du L Y, Bai L, Tang H

机构信息

Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2023 Sep 20;31(9):1004-1008. doi: 10.3760/cma.j.cn501113-20220607-00266.

DOI:10.3760/cma.j.cn501113-20220607-00266
PMID:37872099
Abstract

Liver failure progresses quickly with high mortality. Non-biological artificial liver support system therapy is one of the important treatments for patients with liver failure. The basic techniques of non-biological artificial liver support system therapy include plasma exchange, plasma adsorption and continuous renal replacement therapy. In this paper, the effect and choice of these basic techniques, the treatment timing, the possible patients who may benefit, and the existing problems are summarized and discussed. We hope to provide a reference for the rational use of non-biological artificial liver support system therapy in clinical practice.

摘要

肝衰竭进展迅速,死亡率高。非生物人工肝支持系统治疗是肝衰竭患者的重要治疗方法之一。非生物人工肝支持系统治疗的基本技术包括血浆置换、血浆吸附和连续性肾脏替代治疗。本文对这些基本技术的疗效与选择、治疗时机、可能受益的患者以及存在的问题进行了总结和讨论。我们希望为临床实践中合理应用非生物人工肝支持系统治疗提供参考。

相似文献

1
[Research progress of non-biological artificial liver support system therapy for paitents with liver failure].[肝衰竭患者非生物型人工肝支持系统治疗的研究进展]
Zhonghua Gan Zang Bing Za Zhi. 2023 Sep 20;31(9):1004-1008. doi: 10.3760/cma.j.cn501113-20220607-00266.
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Artificial liver support at present and in the future.当前及未来的人工肝支持
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[Economic evaluation of plasma exchange combined with dual plasma adsorption therapy for early, mid and late stage liver failure].血浆置换联合双重血浆吸附疗法治疗早、中、晚期肝衰竭的经济学评价
Zhonghua Gan Zang Bing Za Zhi. 2020 May 20;28(5):434-440. doi: 10.3760/cma.j.cn501113-20190122-00025.
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[Changes and perspectives of non-biological artificial liver treatment].[非生物型人工肝治疗的变化与展望]
Zhonghua Gan Zang Bing Za Zhi. 2017 Sep 20;25(9):646-650. doi: 10.3760/cma.j.issn.1007-3418.2017.09.002.
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Artificial liver support system for fulminant hepatic failure as bridge-use to living donor liver transplantation.
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[Model selection and curative effect judgment criteria for artificial liver in the treatment of liver failure].
Zhonghua Gan Zang Bing Za Zhi. 2022 Feb 20;30(2):127-130. doi: 10.3760/cma.j.cn501113-20220108-00008.
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[Liver support systems today].[当今的肝脏支持系统]
Orv Hetil. 2009 Dec 20;150(51):2299-307. doi: 10.1556/OH.2009.28769.
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Artificial liver support system in China: a review over the last 30 years.中国的人工肝支持系统:过去30年回顾
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引用本文的文献

1
Effects of the support system combined with Chinese medicine on postoperative gastrointestinal recovery in patients with liver cancer.支持系统联合中药对肝癌患者术后胃肠道恢复的影响
World J Gastrointest Oncol. 2025 Aug 15;17(8):105267. doi: 10.4251/wjgo.v17.i8.105267.
2
Effect of plasma adsorption and low-volume plasma exchange on intracranial pressure in acute-on-chronic liver failure: a prospective observational study.血浆吸附和小容量血浆置换对慢性肝衰竭急性发作患者颅内压的影响:一项前瞻性观察研究。
BMC Gastroenterol. 2025 Jul 31;25(1):545. doi: 10.1186/s12876-025-04139-9.
3
Association between volume of processed plasma and total bilirubin reduction during plasma adsorption for severe liver disease.
重症肝病血浆吸附过程中处理血浆量与总胆红素降低之间的关联
Eur J Med Res. 2025 Mar 15;30(1):175. doi: 10.1186/s40001-025-02419-4.