Department of Pain,The Affiliated Nanchong Central Hospital of North Sichuan Medical College, 97, South Renmin Road, Shunqing District, Nanchong, Sichuan, China.
Department of Pharmacy, Sichuan Nanchong Mental Health center, The Second People's Hospital of Nanchong, Nanchong, Sichuan, China.
BMC Neurol. 2023 Oct 23;23(1):384. doi: 10.1186/s12883-023-03415-z.
This study aimed to investigate the differences in the effectiveness of percutaneous radiofrequency thermocoagulation (PRT) and microvascular decompression (MVD) in treating glossopharyngeal neuralgia (GPN).
Medical records of patients were reviewed to investigate their baseline characteristics and immediate postoperative prognosis. Long-term outcomes of these patients were obtained through telephone interviews. Visual analog scale (VAS) and Pittsburgh sleep quality index (PSQI) scores at 1 day and 1, 4, 12, 24, and 48 weeks after surgery were compared between the MVD and PRT groups, in addition to complete pain relief rate, effective rate, adverse reactions, length of hospital stay, and economic indicators.
The VAS and PSQI scores of the two groups at 1 day and 1, 4, 12, 24, and 48 weeks after surgery were significantly lower (P < 0.05) than those before surgery. At 48 weeks, the complete remission rate was significantly higher (P < 0.05) in the MVD group than in PRT group. No significant difference in adverse reactions was observed between the two groups. The length of hospital stay, operative time, and cost were significantly higher (P < 0.05) in the MVD group than in the PRT group.
Both PRT and MVD can significantly reduce patients' degree of pain and improve their sleep quality. In the medium term, MVD is better than PRT in terms of the complete curative effect. In young patients with GPN, MVD is more often recommended than PRT; however, MVD is costlier than PRT.
本研究旨在探讨经皮射频热凝术(PRT)和微血管减压术(MVD)治疗舌咽神经痛(GPN)的效果差异。
回顾性分析患者的病历资料,调查其基线特征和术后即刻预后。通过电话访谈获取这些患者的长期预后。比较 MVD 组和 PRT 组患者术后 1 天、1、4、12、24 和 48 周时视觉模拟量表(VAS)和匹兹堡睡眠质量指数(PSQI)评分,以及完全缓解率、有效率、不良反应、住院时间和经济指标。
两组患者术后 1 天及 1、4、12、24 和 48 周时 VAS 和 PSQI 评分均明显低于术前(P < 0.05)。术后 48 周时,MVD 组完全缓解率明显高于 PRT 组(P < 0.05)。两组不良反应发生率无明显差异。MVD 组住院时间、手术时间和费用均明显高于 PRT 组(P < 0.05)。
PRT 和 MVD 均可显著减轻患者疼痛程度,改善睡眠质量。在中期,MVD 的完全疗效优于 PRT。对于年轻的 GPN 患者,MVD 比 PRT 更常用;然而,MVD 比 PRT 更昂贵。