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一只怀孕母猫移除地洛瑞林植入物后成功分娩并哺乳。

Successful parturition and lactation after a deslorelin implant removal in a pregnant cat.

作者信息

Paganotto Alessandra, Truttmann Annouck, Rosset Émilie

机构信息

VetAgro Sup, Université de Lyon, Marcy l'Etoile, France.

Clinique Vétérinaire des Gratte-Ciel, Villeurbanne, France.

出版信息

JFMS Open Rep. 2023 Oct 21;9(2):20551169231201606. doi: 10.1177/20551169231201606. eCollection 2023 Jul-Dec.

DOI:10.1177/20551169231201606
PMID:37873522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10590539/
Abstract

CASE SUMMARY

The aim of this clinical case presentation was to describe the effect of a 4.7 mg deslorelin implant placement in a pregnant queen during the second half of gestation, and the consequences of its removal on the pregnancy and parturition. A 5-year-old female cat exhibiting nesting behaviour and weight gain 10 days after placement of a deslorelin implant was presented for examination. Gestation was confirmed on ultrasound, with two well-formed kittens of a gestational age of approximately 7 weeks. The deslorelin implant placed on the umbilicus was removed 1 week later. No change in the pregnancy was observed after removal of the implant. The fetuses showed no signs of distress on ultrasound and radiography examination 4 days after removal of the implant. One week after implant removal, the queen naturally delivered two healthy kittens. The queen showed maternal behaviour with normal milk production.

RELEVANCE AND NOVEL INFORMATION

In the light of the lack of literature on implant injection and removal in the pregnant queen, this case report showcases a successful birth of healthy kittens without any subsequent adverse effect on the queen. Further study is needed to assess the safety of implant removal during pregnancy and potential use as a means to induce fertile oestrus in the queen.

摘要

病例摘要

本临床病例报告的目的是描述在妊娠后半期给怀孕母猫植入4.7毫克醋酸去甲雄三烯醇酮的效果,以及取出该植入物对妊娠和分娩的影响。一只5岁雌性猫在植入醋酸去甲雄三烯醇酮植入物10天后出现筑巢行为并体重增加,前来接受检查。经超声检查确认妊娠,有两只发育良好、胎龄约7周的小猫。1周后取出置于脐部的醋酸去甲雄三烯醇酮植入物。取出植入物后未观察到妊娠情况有变化。取出植入物4天后,超声和X线检查显示胎儿无窘迫迹象。取出植入物1周后,母猫自然分娩出两只健康小猫。母猫表现出母性行为且产奶正常。

相关性及新信息

鉴于缺乏关于怀孕母猫植入物注射和取出的文献,本病例报告展示了健康小猫的成功出生,且对母猫没有任何后续不良影响。需要进一步研究以评估孕期取出植入物的安全性,以及其作为诱导母猫发情手段的潜在用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed01/10590539/6bf8198b3147/10.1177_20551169231201606-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed01/10590539/4b9b9ea788a8/10.1177_20551169231201606-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed01/10590539/6bf8198b3147/10.1177_20551169231201606-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed01/10590539/4b9b9ea788a8/10.1177_20551169231201606-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed01/10590539/6bf8198b3147/10.1177_20551169231201606-fig2.jpg

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本文引用的文献

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J Feline Med Surg. 2023 May;25(5):1098612X231171406. doi: 10.1177/1098612X231171406.
2
The function of the pituitary-testicular axis in dogs prior to and following surgical or chemical castration with the GnRH-agonist deslorelin.促性腺激素释放激素激动剂地洛瑞林对犬进行手术或化学去势前后垂体-睾丸轴的功能。
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控制女王的生殖能力:掌握生殖药物的使用以调控周期性。
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Resumption of ovarian activity following removal of a 4.7 mg deslorelin implant in queens.母猫去势后,取出 4.7 毫克地洛瑞林埋植剂,卵巢活动恢复。
Reprod Domest Anim. 2022 Jan;57(1):3-9. doi: 10.1111/rda.14023. Epub 2021 Oct 10.
5
Manipulation of the oestrous cycle of the bitch-what works… for now.母犬发情周期的调控——目前有效的方法
Reprod Domest Anim. 2018 Nov;53 Suppl 3:44-52. doi: 10.1111/rda.13364.
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Postponement of puberty in queens treated with deslorelin.使用地洛瑞林治疗的蜂王青春期延迟。
J Feline Med Surg. 2017 Dec;19(12):1224-1230. doi: 10.1177/1098612X16688406. Epub 2017 Feb 14.
7
First deliveries after estrus induction using deslorelin and endoscopic transcervical insemination in the queen.使用地洛瑞林诱导发情并经内窥镜经宫颈授精后,母猫的首次分娩情况。
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Effectiveness of deslorelin acetate subcutaneous implantation in a domestic queen with after-spaying urinary incontinence.醋酸地洛瑞林皮下植入对一只绝育后出现尿失禁的家猫的有效性。
J Feline Med Surg. 2014 Apr;16(4):366-8. doi: 10.1177/1098612X13498250. Epub 2013 Jul 19.
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Treatment of queens in estrus and after estrus with a GnRH-agonist implant containing 4.7 mg deslorelin; hormonal response, duration of efficacy, and reversibility.用含有 4.7 毫克地洛瑞林的 GnRH 激动剂埋植剂治疗发情期和发情后期的母犬;激素反应、疗效持续时间和可逆性。
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