Rahbarian Yazdi Farhad, Mehrad-Majd Hassan, Gholami Sepideh, Hassanpour Mohammad, Rezaee Hamid, Abouei Mehrizi Mohammadali, Pakbaz Mehdi, Keykhosravi Ehsan
Arch Bone Jt Surg. 2023;11(10):635-640. doi: 10.22038/ABJS.2023.63374.3059.
Effective postoperative pain control in microdiscectomy surgery is crucial to managing the disease and improving the patient's quality of life. Therefore, this study aimed to assess the potential effectiveness of 2% lidocaine in reducing pain immediately after discectomy surgery.
A total of 60 patients who underwent microdiscectomy surgery were enrolled in this randomized clinical trial study. They were randomly assigned to three groups: one group received lidocaine just before the incision, another group received lidocaine just before closing the incision, and the third group served as the control. Pain scores were measured at 1, 2, 3, 4, 8, and 12 h after the surgery using a Visual Analogue Scale.
The demographic and clinical characteristics of the study population, including age, weight, length of surgery, gender, and history of diabetes, hypertension, and previous surgery, were comparable across all three groups (P>0.05). There was a significant reduction in pain scores over time in the groups that received lidocaine before (P<0.001) and during surgery (P=0.002). Moreover, there were significant differences in pain scores at all time points among the three groups. Both groups receiving lidocaine showed significantly lower pain scores than the control group (Pbefore surgery=0.005 and Pduring surgery<0.001). However, no significant difference was observed between the groups receiving lidocaine (P=0.080).
These findings highlight the effectiveness of a local injection of 2% lidocaine either before or during the surgery in managing post-incisional surgical pain after discectomy.
在显微椎间盘切除术手术中,有效的术后疼痛控制对于疾病管理和提高患者生活质量至关重要。因此,本研究旨在评估2%利多卡因在椎间盘切除术后立即减轻疼痛方面的潜在效果。
共有60例行显微椎间盘切除术的患者纳入本随机临床试验研究。他们被随机分为三组:一组在切口前接受利多卡因,另一组在切口关闭前接受利多卡因,第三组作为对照组。术后1、2、3、4、8和12小时使用视觉模拟量表测量疼痛评分。
研究人群的人口统计学和临床特征,包括年龄、体重、手术时长、性别以及糖尿病、高血压和既往手术史,在所有三组中均具有可比性(P>0.05)。术前(P<0.001)和术中(P=0.002)接受利多卡因的组疼痛评分随时间显著降低。此外,三组在所有时间点的疼痛评分均存在显著差异。接受利多卡因的两组疼痛评分均显著低于对照组(术前P=0.005,术中P<0.001)。然而,接受利多卡因的两组之间未观察到显著差异(P=0.080)。
这些发现突出了手术前或手术期间局部注射2%利多卡因在管理椎间盘切除术后切口疼痛方面的有效性。