Chapman S H, LaPlante M P, Wilensky G
Soc Secur Bull. 1986 Oct;49(10):24-48.
There are several research issues which need further exploration if we are to better understand the implications of what appears to be increased levels of morbidity. Three general areas require additional research: the time of onset of chronic illness, the progression rate of illness, and the overlap and interaction between chronic and non-chronic conditions as well as multiple chronic conditions in a single individual. A major reason for the present uncertainty about morbidity is that information is unavailable regarding the incidence of chronic illness. However, incidence of chronic disease is difficult to measure unless there are either clear clinical indications or functional limitations. Work by survey researchers in defining initial reports of functional limitations associated with chronic illness would be very helpful. Furthermore, an understanding of incidence is necessary to further our understanding of the rate of progression of illness. The concept of a progression rate of illness makes sense only if we can have agreed upon measures of the onset of the illness. Both of these issues clearly require the use of longitudinal data. In fact any serious attempt to predict changes in health status over time as well as to relate changing patterns of mortality with changing patterns of morbidity will require a longitudinal data base. The difficulty in establishing a longitudinal data base is not only the time and expense of follow given set of individuals over a prolonged period of time, but also the problem of having a sample large enough to include individuals with specific chronic conditions of illness. One way to resolve the problem of sufficient sample size may be to do a combined survey which includes both a national probability sample of individuals as well as a sample of individuals with specific chronic diseases. Monitoring a group of individuals known to have specific chronic conditions would provide information about the progression and impact of the disease over time. Including a national probability sample of the entire population would provide information on the impact over time of changing health conditions for the entire population. While screening for specific conditions is an expensive procedure, it is likely to be far cheaper than including a sample size large enough to provide reliable estimates for specific conditions based on a national probability sample. Because the effects of postponed social security benefit eligibility will not be felt for many years, the opportunity for fruitful research is great. For now, we will summarize what we know from current research.
如果我们想要更好地理解发病率上升所带来的影响,就有几个研究问题需要进一步探索。有三个总体领域需要更多研究:慢性病的发病时间、疾病的进展速度,以及慢性病与非慢性病之间以及个体身上多种慢性病之间的重叠与相互作用。目前发病率存在不确定性的一个主要原因是缺乏关于慢性病发病率的信息。然而,除非有明确的临床指征或功能受限情况,否则慢性病的发病率很难测量。调查研究人员在界定与慢性病相关的功能受限初始报告方面所做的工作会非常有帮助。此外,了解发病率对于加深我们对疾病进展速度的理解是必要的。只有当我们能够就疾病的发病衡量标准达成一致时,疾病进展速度这一概念才有意义。这两个问题显然都需要使用纵向数据。事实上,任何认真尝试预测健康状况随时间的变化,以及将死亡率的变化模式与发病率的变化模式联系起来的努力,都需要一个纵向数据库。建立纵向数据库的困难不仅在于长时间跟踪特定人群所需的时间和费用,还在于要有足够大的样本量以纳入患有特定慢性病的个体。解决样本量足够大这一问题的一种方法可能是进行一项综合调查,既包括全国个体概率样本,也包括患有特定慢性病的个体样本。监测一组已知患有特定慢性病的个体将提供有关疾病随时间的进展和影响的信息。纳入全国整个人口的概率样本将提供有关随时间变化的健康状况对整个人口影响的信息。虽然针对特定疾病进行筛查是一项昂贵的程序,但它可能远比基于全国概率样本纳入足够大的样本量以提供特定疾病可靠估计要便宜得多。由于推迟社会保障福利资格的影响在很多年内都不会显现,富有成效的研究机会很大。目前,我们将总结我们从当前研究中所了解的情况。