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ADP: the missing link between thrombosis and hemolysis.

作者信息

Gerber Gloria F, Brodsky Robert A

机构信息

Division of Hematology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD.

出版信息

Blood Adv. 2023 Oct 24;7(20):6364-6366. doi: 10.1182/bloodadvances.2023011186.

DOI:10.1182/bloodadvances.2023011186
PMID:37874560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10625892/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089e/10625892/cdfb3a5f79c7/BLOODA_ADV-2023-011186-C-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089e/10625892/cdfb3a5f79c7/BLOODA_ADV-2023-011186-C-gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/089e/10625892/cdfb3a5f79c7/BLOODA_ADV-2023-011186-C-gr1.jpg

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Thrombosis in Paroxysmal Nocturnal Hemoglobinuria (PNH): From Pathogenesis to Treatment.阵发性睡眠性血红蛋白尿症（PNH）中的血栓形成：从发病机制到治疗。
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本文引用的文献

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Complement and platelets: prothrombotic cell activation requires membrane attack complex-induced release of danger signals.补体与血小板：促血栓形成的细胞活化需要膜攻击复合物诱导释放危险信号。
Blood Adv. 2023 Oct 24;7(20):6367-6380. doi: 10.1182/bloodadvances.2023010817.
2
A 15-year, single institution experience of anticoagulation management in paroxysmal nocturnal hemoglobinuria patients on terminal complement inhibition with history of thromboembolism.一项为期15年的单机构经验，涉及阵发性夜间血红蛋白尿患者在接受终末补体抑制治疗且有血栓栓塞病史时的抗凝管理。
Am J Hematol. 2022 Feb 1;97(2):E59-E62. doi: 10.1002/ajh.26414. Epub 2021 Nov 29.
3
Complementopathies and precision medicine.
补体系统相关疾病与精准医学
J Clin Invest. 2020 May 1;130(5):2152-2163. doi: 10.1172/JCI136094.
4
Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria.阵发性夜间血红蛋白尿症中的血栓形成并不需要显著的溶血。
Haematologica. 2019 Mar;104(3):e94-e96. doi: 10.3324/haematol.2018.198846. Epub 2018 Oct 4.
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CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis.CD55缺乏、早发性蛋白丢失性肠病与血栓形成
N Engl J Med. 2017 Jul 6;377(1):52-61. doi: 10.1056/NEJMoa1615887. Epub 2017 Jun 28.
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Reincarnation of ancient links between coagulation and complement.凝血与补体之间古老联系的再现。
J Thromb Haemost. 2015 Jun;13 Suppl 1:S121-32. doi: 10.1111/jth.12950.
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The complement system and adverse pregnancy outcomes.补体系统与不良妊娠结局
Mol Immunol. 2015 Sep;67(1):56-70. doi: 10.1016/j.molimm.2015.02.030. Epub 2015 Mar 21.
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Blood. 2011 Jun 23;117(25):6786-92. doi: 10.1182/blood-2011-02-333997. Epub 2011 Apr 1.
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Blood. 2007 Oct 1;110(7):2423-31. doi: 10.1182/blood-2007-01-070631. Epub 2007 May 29.
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