Denison D M, Morgan M D, Millar A B
Thorax. 1986 Aug;41(8):620-8. doi: 10.1136/thx.41.8.620.
This study was intended to discover how well computed tomography could recover the volume and weight of lung like foams in a body like shell, and then how well it could recover the volume and weight of the lungs in supine man. Model thoraces were made with various loaves of bread submerged in water. Computed tomography scans recovered the volume of the model lungs (true volume range 250-12,500 ml) within +0.2 (SD 68) ml and their weights (true range 72-3125 g) within +30 (78) g. Scans also recovered successive injections of 50 ml of water, within +/- 5 ml. Scans in 12 healthy supine men recovered their vital capacities, total lung capacities (TLC), and predicted tissue volumes with comparable accuracy. At total lung capacity the mean tissue volume of single lungs was 431 (64) ml and at residual volume (RV) it was 427 (63) ml. Tissue volume was then used to match inspiratory and expiratory slices and calculate regional ventilation. Throughout the mid 90% of lung the RV/TLC ratio was fairly constant--mean 21% (5%). New methods of presenting such regional data graphically and automatically are also described.
本研究旨在探究计算机断层扫描在模拟人体躯壳中恢复肺样泡沫的体积和重量的效果如何，进而探究其在仰卧位人体中恢复肺体积和重量的效果如何。用各种浸在水中的面包制作模型胸廓。计算机断层扫描能在±0.2（标准差68）毫升范围内恢复模型肺的体积（真实体积范围为250 - 12500毫升），在±30（78）克范围内恢复其重量（真实范围为72 - 3125克）。扫描还能在±5毫升范围内恢复连续注入的50毫升水。对12名健康仰卧位男性进行的扫描以相当的准确度恢复了他们的肺活量、肺总量（TLC）以及预测的组织体积。在肺总量时，单肺的平均组织体积为431（64）毫升，在残气量（RV）时为427（63）毫升。然后用组织体积来匹配吸气和呼气切片并计算局部通气。在肺的中间90%区域，RV/TLC比值相当恒定——平均为21%（5%）。还描述了以图形方式自动呈现此类局部数据的新方法。
