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[知识图谱在医学领域的应用概述]

[Overview of the application of knowledge graphs in the medical field].

作者信息

Wang Caiyun, Zheng Zengliang, Cai Xiaoqiong, Huang Jihan, Su Qianmin

机构信息

College of Electrical and Electronic Engineering, Shanghai University Of Engineering Science, Shanghai 201620, P. R. China.

Center for Drug Clinical Research, Shanghai University of Chinese Medicine, shanghai 201203, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023 Oct 25;40(5):1040-1044. doi: 10.7507/1001-5515.202204016.

DOI:10.7507/1001-5515.202204016
PMID:37879936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10600424/
Abstract

With the booming development of medical information technology and computer science, the medical services industry is gradually transiting from information technology to intelligence. The medical knowledge graph plays an important role in intelligent medical applications such as knowledge questions and answers and intelligent diagnosis, and is a key technology for promoting wise medical care and the basis for intelligent management of medical information. In order to fully exploit the great potential of knowledge graphs in the medical field, this paper focuses on five aspects: inter-drug relationship discovery, assisted diagnosis, personalized recommendation, decision support and intelligent prediction. The latest research progress on medical knowledge graphs is introduced, and relevant suggestions are made in light of the current challenges and problems faced by medical knowledge graphs to provide reference for promoting the wide application of medical knowledge graphs.

摘要

随着医学信息技术和计算机科学的蓬勃发展,医疗服务行业正逐步从信息化向智能化转变。医学知识图谱在知识问答、智能诊断等智能医疗应用中发挥着重要作用,是推动智慧医疗的关键技术和医疗信息智能管理的基础。为了充分挖掘知识图谱在医学领域的巨大潜力,本文重点从药物相互作用关系发现、辅助诊断、个性化推荐、决策支持和智能预测五个方面展开研究。介绍了医学知识图谱的最新研究进展,并针对医学知识图谱目前面临的挑战和问题提出了相关建议,以期为推动医学知识图谱的广泛应用提供参考。

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Multi-layer information fusion based on graph convolutional network for knowledge-driven herb recommendation.基于图卷积网络的多层信息融合用于知识驱动的草药推荐。
Neural Netw. 2022 Feb;146:1-10. doi: 10.1016/j.neunet.2021.11.010. Epub 2021 Nov 16.
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Expert-Augmented Computational Drug Repurposing Identified Baricitinib as a Treatment for COVID-19.专家增强型计算药物重新定位确定巴瑞替尼可用于治疗新冠肺炎。
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Brief Bioinform. 2021 Nov 5;22(6). doi: 10.1093/bib/bbab293.
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Design and Evaluation of a Prescription Drug Monitoring Program for Chinese Patent Medicine based on Knowledge Graph.基于知识图谱的中成药处方药监测项目设计与评估
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Drug Repurposing for the Treatment of COVID-19: A Knowledge Graph Approach.药物再利用治疗新冠肺炎:一种知识图谱方法
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EHR-Oriented Knowledge Graph System: Toward Efficient Utilization of Non-Used Information Buried in Routine Clinical Practice.面向电子病历的知识图谱系统:挖掘常规临床实践中未被利用的信息。
IEEE J Biomed Health Inform. 2021 Jul;25(7):2463-2475. doi: 10.1109/JBHI.2021.3085003. Epub 2021 Jul 27.
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Knowledge graphs and their applications in drug discovery.知识图谱及其在药物发现中的应用。
Expert Opin Drug Discov. 2021 Sep;16(9):1057-1069. doi: 10.1080/17460441.2021.1910673. Epub 2021 Apr 12.
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