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比较指压与氯硝西泮片对血液透析患者睡眠质量的影响:一项随机对照试验。

Comparing the Effects of Acupressure and Clonazepam Tablets on Sleep Quality of Hemodialysis Patients: A Randomized Controlled Trial.

作者信息

Ezzati Mansooreh, Bagheri-Nesami Masoumeh, Setareh Javad, Moosazadeh Mahmood, Espahbodi Fatemeh, Esmaeili Ahangarkelai Nadali

机构信息

Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.

Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Iran J Psychiatry. 2023 Oct;18(4):455-465. doi: 10.18502/ijps.v18i4.13632.

Abstract

The current study aimed to compare the impact of acupressure and clonazepam tablets on the quality of sleep in hemodialysis patients in light of the rising prevalence of chronic kidney disease (CKD), the high prevalence of sleep disturbance in these patients, and the side effects of hypnotic drugs. A total of 60 patients were selected for this randomized, controlled clinical trial and randomly assigned to two groups. For two weeks during the researcher's evening shift, one group received acupressure (six spots bilaterally for three minutes each day). The opposing group was administered clonazepam tablets (0.5 mg) for two weeks. The Pittsburgh Sleep Quality Index (PSQI), which measures sleep quality, was used to compare sleep in the two groups before and after the intervention. There was no statistically significant difference between the two groups prior to the intervention (P = 0.75) in terms of the mean pre-intervention PSQI scores for the acupressure and clonazepam groups, which were 15.83 ± 1.51 and 16.17 ± 0.91, respectively. However, the average PSQI scores after the intervention in the clonazepam and acupressure groups were 13.25 ± 2.88 and 8.97 ± 4.29, respectively, indicating a statistically significant difference (P < 0.0001). Both the acupressure and the clonazepam groups showed improvements in their post-intervention sleep quality among the patients. However, when the percentage changed in the mean scores of the total score and all of the PSQI components were calculated for each group, it became clear that acupressure was more effective at enhancing sleep than clonazepam tablets. The findings of the present investigation demonstrate that acupressure has a greater impact on patients' sleep quality compared to clonazepam tablets. Depending on the circumstances, acupressure can be used as a simple, safe, and non-drug way to enhance hemodialysis patients' quality of sleep.

摘要

鉴于慢性肾脏病(CKD)患病率不断上升、这些患者睡眠障碍患病率高以及催眠药物的副作用,本研究旨在比较指压疗法和氯硝西泮片对血液透析患者睡眠质量的影响。本随机对照临床试验共选取了60例患者,并随机分为两组。在研究人员值夜班的两周时间里,一组接受指压疗法(双侧六个穴位,每天每个穴位按压三分钟)。另一组服用氯硝西泮片(0.5毫克),为期两周。采用匹兹堡睡眠质量指数(PSQI)来衡量睡眠质量,以比较两组在干预前后的睡眠情况。在干预前,指压疗法组和氯硝西泮组的平均干预前PSQI得分分别为15.83±1.51和16.17±0.91,两组之间无统计学显著差异(P = 0.75)。然而,氯硝西泮组和指压疗法组干预后的平均PSQI得分分别为13.25±2.88和8.97±4.29,表明存在统计学显著差异(P < 0.0001)。指压疗法组和氯硝西泮组患者的干预后睡眠质量均有所改善。然而,当计算每组总分及所有PSQI成分的平均得分变化百分比时,很明显指压疗法在改善睡眠方面比氯硝西泮片更有效。本调查结果表明,与氯硝西泮片相比,指压疗法对患者睡眠质量的影响更大。根据具体情况,指压疗法可作为一种简单、安全且非药物的方法来提高血液透析患者的睡眠质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b51d/10593989/b176a8723b07/IJPS-18-455-g001.jpg

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