Department of Kinesiology, College of Health and Human Sciences, KS State University, Manhattan, KS, USA.
Lafene Health Center, Kansas State University, Manhattan, KS, USA.
Ann Med. 2023;55(2):2269586. doi: 10.1080/07853890.2023.2269586. Epub 2023 Oct 26.
Athletes are susceptible to acute respiratory tract infections, including SARS-CoV-2, which can affect cardiovascular function. We aimed to evaluate the impact of COVID-19 infection and quarantine on cardiac function in male and female collegiate athletes.
We conducted a single-center, prospective, case-control study and performed transthoracic echocardiography in a diverse group of convalescent SARS-CoV-2-positive athletes following a 10-14-day quarantine, matched to non-SARS-CoV-2 athletes. Data collection occurred from August 1, 2020, to May 31, 2021.
We evaluated 61 SARS-CoV-2-positive athletes (20 ± 1 years, 39% female) and 61 controls (age 20 ± 2 years, 39% female). Echocardiography in SARS-CoV-2-positive athletes was performed on average 40 ± 38 days after infection diagnosis. All SARS-CoV-2-positive athletes had clinically normal systolic left ventricular function (LVEF > 50%). However, SARS-CoV-2-positive athletes exhibited mildly lower LVEF compared to controls (65 ± 6% vs. 72 ± 8%, respectively, < 0.001), which remained significant when evaluated separately for female and male athletes. Sub-analysis revealed these differences occurred only when imaging occurred within a mean average of 27 days of infection, with a longer recovery period (≥27 days) resulting in no differences. SARS-CoV-2-positive male athletes exhibited higher left ventricular end-diastolic volume and mitral filling velocities compared to male controls.
Our study reveals unique sex-specific cardiac changes in collegiate athletes following SARS-CoV-2 infection and quarantine compared to controls. Despite a mild reduction in LVEF, which was only observed in the first weeks following infection, no clinically significant cardiac abnormalities were observed. Further research is required to understand if the changes in LVEF are directly attributed to the infection or indirectly through exercise restrictions resulting from quarantine.
运动员易患急性呼吸道感染，包括 SARS-CoV-2，这可能影响心血管功能。我们旨在评估 COVID-19 感染和隔离对男性和女性大学生运动员心脏功能的影响。
我们进行了一项单中心、前瞻性、病例对照研究，对 SARS-CoV-2 感染后进行了 10-14 天隔离的康复期运动员进行了经胸超声心动图检查，并与非 SARS-CoV-2 运动员进行了匹配。数据收集时间为 2020 年 8 月 1 日至 2021 年 5 月 31 日。
我们评估了 61 名 SARS-CoV-2 阳性运动员（20±1 岁，39%为女性）和 61 名对照者（年龄 20±2 岁，39%为女性）。SARS-CoV-2 阳性运动员的超声心动图检查平均在感染诊断后 40±38 天进行。所有 SARS-CoV-2 阳性运动员的左心室收缩功能均正常（LVEF>50%）。然而，与对照组相比，SARS-CoV-2 阳性运动员的 LVEF 略低（分别为 65±6%和 72±8%，均<0.001），当分别评估女性和男性运动员时，这一差异仍然显著。亚组分析表明，这些差异仅发生在影像学检查发生在感染后平均 27 天内，而恢复期较长（≥27 天）则无差异。与男性对照组相比，SARS-CoV-2 阳性男性运动员的左心室舒张末期容积和二尖瓣充盈速度较高。
与对照组相比，我们的研究揭示了 SARS-CoV-2 感染和隔离后大学生运动员中独特的性别特异性心脏变化。尽管 LVEF 略有下降，仅在感染后最初几周观察到，但未观察到临床显著的心脏异常。需要进一步研究以了解 LVEF 的变化是否直接归因于感染，还是间接归因于隔离导致的运动限制。
Zotero 插件
