感染圣路易斯脑炎病毒的小鼠的迟发型超敏反应：反应动力学及免疫调节剂的作用
Delayed-type hypersensitivity responses in mice infected with St. Louis encephalitis virus: kinetics of the response and effects of immunoregulatory agents.
作者信息
Hudson B W, Wolff K, DeMartini J C
出版信息
Infect Immun. 1979 Apr;24(1):71-6. doi: 10.1128/iai.24.1.71-76.1979.
Abstract
Labeled monocyte infiltration techniques have been used to study delayed-type hypersensitivity responses in mice immunized with St. Louis encephalitis virus. A delayed 24- to 48-h inflammatory response occurred 6 to 7 days after immunization. This response can be potentiated by cyclophosphamide treatment, by BCG administration, or by splenectomy. Treatments known to selectivity inhibit T-cell function suppressed the response.
摘要
标记单核细胞浸润技术已被用于研究用圣路易斯脑炎病毒免疫的小鼠的迟发型超敏反应。免疫后6至7天出现延迟24至48小时的炎症反应。这种反应可通过环磷酰胺治疗、卡介苗接种或脾切除术增强。已知选择性抑制T细胞功能的治疗可抑制该反应。
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