Krishnan Abhijith, Deepak C S, Narayan K S
Chemistry and Physics of Materials Unit (CPMU), JNCASR, Bangalore, India.
APL Bioeng. 2023 Oct 24;7(4):046105. doi: 10.1063/5.0156463. eCollection 2023 Dec.
Organic semiconductors are being explored as retinal prosthetics with the prime attributes of bio-compatibility and conformability for seamless integration with the retina. These polymer-based artificial photoreceptor films are self-powered with light-induced signal strength sufficient to elicit neuronal firing events. The molecular aspect of these semiconductors provides wide spectral tunability. Here, we present results from a bulk heterostructure semiconductor blend with a wide spectral response range. This combination elicits clear spiking activity from a developing blind-chick embryonic retina in the subretinal configuration in response to white light. The response is largely triggered by the blue-green spectral regime rather than the red-NIR regime for the present polymer semiconductor layer attributes.
有机半导体正被探索用作视网膜假体，其主要特性是生物相容性和可贴合性，以便与视网膜无缝集成。这些基于聚合物的人工光感受器薄膜是自供电的，其光诱导信号强度足以引发神经元放电事件。这些半导体的分子特性提供了广泛的光谱可调性。在此，我们展示了一种具有宽光谱响应范围的体异质结半导体混合物的结果。这种组合在视网膜下配置中，能使发育中的盲鸡胚胎视网膜对白光产生清晰的尖峰活动。由于当前聚合物半导体层的特性，这种响应主要由蓝绿色光谱区域触发，而非红 - 近红外区域。
