Crowley L V
Am J Gastroenterol. 1986 Dec;81(12):1188-90.
A middle-aged woman developed a postgastric bypass megaloblastic anemia which responded to treatment. She eventually had the bypass reversed 6 1/2 yr after it had been performed. Gastric parietal cell function has remained abnormal almost 3 yr after reversal of the bypass, as demonstrated by abnormal Schilling tests and high serum gastrin levels. Parietal cell antibodies in high titer, but no intrinsic factor antibodies, were demonstrated in her blood. These observations are interpreted as indicating the development of irreversible chronic atrophic gastritis probably related to reflux of bile into the bypassed stomach.
一名中年女性在胃旁路手术后出现巨幼细胞贫血，经治疗后病情好转。最终，在胃旁路手术进行6年半后，她接受了手术逆转。胃旁路手术逆转后近3年，胃壁细胞功能仍异常，这通过异常的希林试验和高血清胃泌素水平得以证实。她的血液中检测到高滴度的壁细胞抗体，但未检测到内因子抗体。这些观察结果被解释为表明可能与胆汁反流至旷置胃有关的不可逆慢性萎缩性胃炎的发生。
