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饲料生物活性化合物与鸡基因组之间的相互作用

The Interaction between Feed Bioactive Compounds and Chicken Genome.

作者信息

Gvozdanović Kristina, Kralik Zlata, Radišić Žarko, Košević Manuela, Kralik Gordana, Djurkin Kušec Ivona

机构信息

Faculty of Agrobiotechnical Sciences Osijek, Josip Juraj Strossmayer University of Osijek, Vladimira Preloga 1, 31000 Osijek, Croatia.

Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, Trg Svetog Trojstva 3, 31000 Osijek, Croatia.

出版信息

Animals (Basel). 2023 May 31;13(11):1831. doi: 10.3390/ani13111831.

Abstract

Consumer demand for high quality and safe foods that will have a positive impact on their health has increased in recent years. Today, it is possible to meet those demands by combining the genetic potential of domestic animals and applying different feeding strategies. Nutrigenomics is one of the "omics" sciences that studies the interaction between nutrients and the genome together with their influence on metabolic and physiological processes in the body. While nutrition of domestic animals is solely based on studying the influence of nutrients on animal health and production traits, nutrigenomics integrates the fields of nutrition, genomics, molecular genetics and bioinformatics. By understanding the molecular relationships between different forms and/or concentrations of nutrients in feed and genes, it is possible to answer the question of how small changes in the diet of farm animals can produce a quality product with positive effects on human health. The aim of this article is to describe how the manipulation of adding different nutrients in the feed affects the expression of different genes in chicken and consequently alters their phenotype.

摘要

近年来,消费者对有益于健康的高品质安全食品的需求有所增加。如今,通过结合家畜的遗传潜力并应用不同的饲养策略,满足这些需求成为可能。营养基因组学是“组学”科学之一,它研究营养素与基因组之间的相互作用及其对体内代谢和生理过程的影响。虽然家畜营养仅基于研究营养素对动物健康和生产性状的影响,但营养基因组学整合了营养、基因组学、分子遗传学和生物信息学等领域。通过了解饲料中不同形式和/或浓度的营养素与基因之间的分子关系,就有可能回答这样一个问题:家畜饮食中的微小变化如何能产生对人类健康有积极影响的优质产品。本文的目的是描述在饲料中添加不同营养素的操作如何影响鸡体内不同基因的表达,进而改变它们的表型。

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