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食管切除术的历史里程碑:从 Torek 到微创方法。

Milestones in the History of Esophagectomy: From Torek to Minimally Invasive Approaches.

机构信息

Department of Thoracic Surgery, Lung Transplantation and Diseases of the Esophagus, Aix-Marseille University, Assistance Publique-Hôpitaux de Marseille, North Hospital, Chemin des Bourrely, 13915 Marseille, France.

出版信息

Medicina (Kaunas). 2023 Oct 7;59(10):1786. doi: 10.3390/medicina59101786.

Abstract

The history of esophagectomy reflects a journey of dedication, collaboration, and technical innovation, with ongoing endeavors aimed at optimizing outcomes and reducing complications. From its early attempts to modern minimally invasive approaches, the journey has been marked by perseverance and innovation. Franz J. A. Torek's 1913 successful esophageal resection marked a milestone, demonstrating the feasibility of transthoracic esophagectomy and the potential for esophageal cancer cure. However, its high mortality rate posed challenges, and it took almost two decades for similar successes to emerge. Surgical techniques evolved with the left thoracotomy, right thoracotomy, and transhiatal approaches, expanding the indications for resection. Mechanical staplers introduced in the early 20th century transformed anastomosis, reducing complications. The advent of minimally invasive techniques in the 1990s aimed to minimize complications while maintaining oncological efficacy. Robot-assisted esophagectomy further pushed the boundaries of minimally invasive surgery. Collaborative efforts, particularly from the Worldwide Esophageal Cancer Collaboration and the Esophageal Complications Consensus Group, standardized reporting and advanced the understanding of outcomes. The introduction of risk prediction models aids in making informed decisions. Despite significant improvements in survival rates and postoperative mortality, anastomotic leaks remain a concern, with recent rates showing an increase. Prevention strategies include microvascular anastomosis and ischemic preconditioning, yet challenges persist.

摘要

食管切除术的历史反映了一个专注、协作和技术创新的历程,不断努力旨在优化结果并减少并发症。从早期的尝试到现代的微创方法,这个历程充满了坚持和创新。弗朗茨·J·A·托雷克(Franz J. A. Torek)于 1913 年成功进行的食管切除术标志着一个里程碑,展示了经胸食管切除术的可行性和治愈食管癌的潜力。然而,其高死亡率带来了挑战,直到近 20 年后才取得类似的成功。手术技术随着左开胸术、右开胸术和经食管裂孔入路的发展而演变,扩大了切除的适应证。20 世纪初引入的机械吻合器改变了吻合术,减少了并发症。20 世纪 90 年代微创技术的出现旨在在保持肿瘤疗效的同时最小化并发症。机器人辅助食管切除术进一步推动了微创外科的发展。协作努力,特别是来自全球食管癌协作组和食管并发症共识小组的努力,标准化了报告并提高了对结果的理解。风险预测模型的引入有助于做出明智的决策。尽管生存率和术后死亡率有了显著提高,但吻合口漏仍然是一个关注点,最近的发生率有所增加。预防策略包括微血管吻合和缺血预处理,但挑战仍然存在。

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