Mohammadnezhad Pouya, Valdés Alberto, Barrientos Ruth E, Ibáñez Elena, Block Jane Mara, Cifuentes Alejandro
Foodomics Laboratory, CIAL, CSIC-UAM, Nicolas Cabrera 9, 28049 Madrid, Spain.
Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 5090000, Chile.
Foods. 2023 Oct 23;12(20):3879. doi: 10.3390/foods12203879.
The Amazonian (Willd.) Kuntze nuts contain a lipidic fraction with health-promoting effects, but little is known about the bioactivity of other constituents. In this study, the lipidic fraction obtained using supercritical fluid extraction (SFE) with CO was chemically characterized by using lipidomics techniques. The SFE-CO residue, named as pracaxi cake, was re-extracted by pressurized liquid extraction following a biorefinery approach. Using a response surface methodology and based on the extraction yield and different assays, two optimum conditions were obtained: 80% and 12.5% of ethanol at 180 °C. Under these conditions, extraction yield and different measurements related to neuroprotection were assessed. Chemical characterization of these extracts suggested the presence of triterpenoid saponins and spermidine phenolamides, which were not previously reported in pracaxi nuts. These results suggest that pracaxi oil extraction by-products are a valuable source of bioactive compounds with neuroprotective potential.
亚马孙（威尔德）昆茨坚果含有具有促进健康作用的脂质部分，但对其他成分的生物活性了解甚少。在本研究中，使用脂质组学技术对采用超临界流体萃取（SFE）和二氧化碳获得的脂质部分进行了化学表征。超临界流体萃取-二氧化碳残渣，即称作普拉卡希饼，按照生物炼制方法通过加压液体萃取进行再提取。采用响应面法并基于提取率和不同测定方法，获得了两个最佳条件：180℃下80%和12.5%的乙醇。在这些条件下，评估了提取率和与神经保护相关的不同测量值。这些提取物的化学表征表明存在三萜皂苷和亚精胺酚酰胺，这在普拉卡希坚果中以前未曾有过报道。这些结果表明，普拉卡希油提取副产物是具有神经保护潜力的生物活性化合物的宝贵来源。
