Department of Nutrition, Chung Shan Medical University, 110, Section 1, Jianguo North Road, Taichung 40201, Taiwan.
Faculty of Agricultural Technology, Widya Mandala Catholic University Surabaya, Surabaya 60265, Indonesia.
Molecules. 2023 Oct 18;28(20):7150. doi: 10.3390/molecules28207150.
Phytochemicals are plant secondary metabolites that show health benefits for humans due to their bioactivity. There is a huge variety of phytochemicals that have already been identified, and these compounds can act as antimicrobial and neuroprotection agents. Due to their anti-microbial activity and neuroprotection, several phytochemicals might have the potency to be used as natural therapeutic agents, especially for infection and neurodegenerative disease, which have become a global health concern nowadays. According to previous research, there are some connections between infection and neurodegenerative diseases, especially Alzheimer's disease. Hence, this comprehensive review examines different kinds of phytochemicals from natural sources as potential therapeutic agents to reduce infection and improve neurodegenerative disease. An additional large-scale study is needed to establish the connection between infection and neurodegenerative disease and how phytochemicals could improve this condition.
植物化学物质是植物的次生代谢产物,由于其生物活性,对人类健康有益。已经鉴定出了大量的植物化学物质,这些化合物可以作为抗菌和神经保护剂。由于其抗菌活性和神经保护作用,几种植物化学物质可能具有作为天然治疗剂的潜力,特别是对于感染和神经退行性疾病,这些疾病现在已经成为全球健康关注的问题。根据之前的研究,感染和神经退行性疾病之间存在一些联系,特别是阿尔茨海默病。因此,本综述考察了来自天然来源的不同种类的植物化学物质作为潜在的治疗剂,以减少感染和改善神经退行性疾病。需要进行更大规模的研究,以确定感染和神经退行性疾病之间的联系,以及植物化学物质如何改善这种情况。