Trollip Lindy, Alberto Kerry, Makgotloe Aubrey
Department of Ophthalmology, University of Witwatersrand, Johannesburg 2193, South Africa.
Life (Basel). 2023 Sep 28;13(10):1979. doi: 10.3390/life13101979.
Ultrasonographic optic nerve sheath diameter (ONSD) measurement is an accurate, portable, and non-invasive method of detecting raised intracranial pressure that can also reflect dynamic, real-time changes in intracranial pressure fluctuations. Various studies have shown the mean range of ONSD to vary greatly across different population groups. This study aimed to determine the mean ONSD in healthy Black South African adults. In this cross-sectional study, healthy black South African adult participants underwent optic nerve sheath ultrasound of the right eye, with the diameter being measured at 3 mm behind the retina in two different planes. The average of the two measurements was used to find the mean optic nerve sheath diameter. This measurement was compared to that found in a Canadian adult population, and the effect of age, gender, and co-morbidities on ONSD was assessed. A total of 99 participants were included in this study, of which 39 were male and 60 were female. The mean ONSD was found to be 5.1 mm (SD ± 0.33). This value was significantly higher than the mean ONSD observed in the Canadian population ( < 0.001). There was no significant difference found between the mean ONSD in males and females ( = 0.652), and both age and presence of co-morbidities were not found to significantly correlate with ONSD. ( = 0.693 and = 0.974, respectively).
超声测量视神经鞘直径（ONSD）是一种准确、便携且无创的检测颅内压升高的方法，它还能反映颅内压波动的动态实时变化。各种研究表明，不同人群的ONSD平均范围差异很大。本研究旨在确定健康的南非黑人成年人的平均ONSD。在这项横断面研究中，健康的南非黑人成年参与者接受了右眼视神经鞘超声检查，在两个不同平面的视网膜后3毫米处测量直径。将两次测量的平均值用于计算平均视神经鞘直径。将该测量结果与加拿大成年人群的测量结果进行比较，并评估年龄、性别和合并症对ONSD的影响。本研究共纳入99名参与者，其中男性39名，女性60名。发现平均ONSD为5.1毫米（标准差±0.33）。该值显著高于在加拿大人群中观察到的平均ONSD（<0.001）。男性和女性的平均ONSD之间未发现显著差异（=0.652），并且未发现年龄和合并症的存在与ONSD有显著相关性（分别为=0.693和=0.974）。
