结构域III参与牛血清白蛋白N-F转变的直接证据。
Direct evidence for the involvement of domain III in the N-F transition of bovine serum albumin.
作者信息
Khan M Y
出版信息
Biochem J. 1986 May 15;236(1):307-10. doi: 10.1042/bj2360307.
Abstract
The domain III of bovine serum albumin containing residues 377-582 of the protein sequence was isolated and its behaviour in acid solution was studied. The fragment was found to undergo structural transformations over the pH range 3.5-4.5 known to cause N-F transition in serum albumin. On the other hand, an albumin fragment that was devoid of domain III was unable to exhibit such a transition. These results were consistent with a mechanism where N-F transition involves the separation of domain III from the rest of the albumin starts at about pH 4.3 and is completed at pH 3.5.
摘要
分离出了牛血清白蛋白包含蛋白质序列中377 - 582位残基的结构域III，并研究了其在酸性溶液中的行为。发现该片段在pH值3.5 - 4.5范围内会发生结构转变，已知此pH范围会导致血清白蛋白发生N - F转变。另一方面，一个不含结构域III的白蛋白片段无法表现出这种转变。这些结果与一种机制相符，即N - F转变涉及结构域III与白蛋白其余部分的分离，该分离在约pH 4.3时开始，在pH 3.5时完成。
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本文引用的文献
1
[The structure of bovine serum albumin in solution at pH 5,3 and 3,6: study by the absolute central diffusion of x-rays].[pH值为5.3和3.6时溶液中牛血清白蛋白的结构：通过X射线绝对中心扩散进行的研究]
J Mol Biol. 1961 Aug;3:379-92. doi: 10.1016/s0022-2836(61)80051-x.
2
Sequence of residues 400--403 of bovine serum albumin.牛血清白蛋白400 - 403位残基序列。
Biochem J. 1980 Dec 1;191(3):867-8. doi: 10.1042/bj1910867.
3
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4
End group determination.端基测定
Mol Biol Biochem Biophys. 1970;8:25-90. doi: 10.1007/978-3-662-12834-3_3.
5
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Adv Protein Chem. 1968;23:121-282. doi: 10.1016/s0065-3233(08)60401-5.
6
Influence of temperature on the intrinsic viscosities of proteins in random coil conformation.温度对处于无规卷曲构象的蛋白质特性粘度的影响。
Biochemistry. 1974 Jan 15;13(2):245-9. doi: 10.1021/bi00699a003.
7
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