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婴儿巨大腹膜后畸胎瘤伴单侧肾积水:一例报告并文献复习

Large Retroperitoneal Teratoma Presenting with Unilateral Hydronephrosis in an Infant: A Case Report and Review of the Literature.

作者信息

Safaei Negar, Kamran Hooman, Anbardar Mohammad Hossein, Bordbar Mohammadreza, Zekavat Omid Reza, Forooghi Mehdi

机构信息

Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Case Rep Oncol. 2023 Sep 26;16(1):1041-1047. doi: 10.1159/000533829. eCollection 2023 Jan-Dec.

Abstract

Teratoma is a type of germ cell tumor layer that appears in the gonadal, sacrococcygeal, mediastinal, and retroperitoneal regions. Primary retroperitoneal teratoma is rare and asymptomatic but can present with symptoms due to a mass effect on neighboring organs. These tumors have to be considered in the differential diagnosis of a mass in the abdominal cavity of children to distinguish between Wilms' tumor, neuroblastoma, and other intra-abdominal lesions. We presented an infant boy with protrusion of the left upper quadrant of the abdomen and a palpable abdominal mass that had progressively enlarged. An abdominal computed tomography scan revealed a large retroperitoneal cystic, solid mass on the left side of the abdominal cavity, causing pressure on the left ureter. Also, hydronephrosis of the left kidney was seen with a decreased enhancement of the left kidney due to obstruction uropathy. The mass was suspicious on imaging for a retroperitoneal teratoma. The patient underwent laparotomy, and excision of the huge retroperitoneal mass was done. The final diagnosis was an immature teratoma grade 3, and the patient was discharged in good condition. Retroperitoneal teratomas are rare tumors in infants. These tumors would be an incident diagnosis or diagnosed by the mass effect of giant tumors on other organs. They must be considered in the differential diagnosis of intra-abdominal tumors in children. Hydronephrosis and obstructive uropathy can be rare consequences of the mass effects of these tumors.

摘要

畸胎瘤是一种生殖细胞肿瘤,出现在性腺、骶尾部、纵隔和腹膜后区域。原发性腹膜后畸胎瘤罕见且无症状,但可因对邻近器官的占位效应而出现症状。在儿童腹腔肿块的鉴别诊断中必须考虑这些肿瘤,以区分肾母细胞瘤、神经母细胞瘤和其他腹腔内病变。我们报告了一名男婴,其左上腹突出,可触及腹部肿块,且肿块逐渐增大。腹部计算机断层扫描显示腹腔左侧有一个巨大的腹膜后囊实性肿块,对左输尿管造成压迫。此外,可见左肾积水,由于梗阻性肾病,左肾强化减弱。该肿块在影像学上怀疑为腹膜后畸胎瘤。患者接受了剖腹手术,并切除了巨大的腹膜后肿块。最终诊断为3级未成熟畸胎瘤,患者出院时情况良好。腹膜后畸胎瘤在婴儿中是罕见肿瘤。这些肿瘤可能是偶然诊断出来的,或者是通过巨大肿瘤对其他器官的占位效应诊断出来的。在儿童腹腔内肿瘤的鉴别诊断中必须考虑到它们。肾积水和梗阻性肾病可能是这些肿瘤占位效应的罕见后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e99/10601827/50b9b2561a75/cro-2023-0016-0001-533829_F01.jpg

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