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Influence of aging, mitochondrial dysfunction, and inflammation on Parkinson's disease.

作者信息

Cossu Davide, Hattori Nobutaka

机构信息

Department of Neurology, Juntendo University, Tokyo, Japan (Cossu D, Hattori N).

Department of Biomedical Sciences, Sassari University, Sassari, Italy (Cossu D).

出版信息

Neural Regen Res. 2024 Jun 1;19(6):1197-1198. doi: 10.4103/1673-5374.385873. Epub 2023 Sep 22.

DOI:10.4103/1673-5374.385873
PMID:37905862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11467919/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8420/11467919/05489a91c196/NRR-19-1197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8420/11467919/05489a91c196/NRR-19-1197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8420/11467919/05489a91c196/NRR-19-1197-g001.jpg

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本文引用的文献

1
Is Glial Dysfunction the Key Pathogenesis of -Linked Parkinson's Disease?胶质细胞功能障碍是路易体相关性帕金森病的关键发病机制吗?
Biomolecules. 2023 Jan 15;13(1):178. doi: 10.3390/biom13010178.
2
Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice.PINK1 敲除小鼠实验性自身免疫性脑脊髓炎的年龄相关免疫调节。
Front Immunol. 2022 Nov 17;13:1036680. doi: 10.3389/fimmu.2022.1036680. eCollection 2022.
3
β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats.
基因预测的维生素 D 水平与帕金森病之间不存在关联。
PLoS One. 2024 Nov 15;19(11):e0313631. doi: 10.1371/journal.pone.0313631. eCollection 2024.
4
Exploring the complexity of EEG patterns in Parkinson's disease.探索帕金森病脑电图模式的复杂性。
Geroscience. 2025 Feb;47(1):837-849. doi: 10.1007/s11357-024-01277-y. Epub 2024 Jul 13.
5
Transcriptome Study of rd1Mouse Brain and Association with Parkinson's Disease.rd1小鼠大脑的转录组研究及其与帕金森病的关联
ACS Omega. 2024 Jun 6;9(24):25756-25765. doi: 10.1021/acsomega.3c09938. eCollection 2024 Jun 18.
β2微球蛋白会加重大鼠中风后的神经炎症、脑损伤和认知障碍。
Neural Regen Res. 2023 Mar;18(3):603-608. doi: 10.4103/1673-5374.350204.
4
Molecular genetics of Parkinson's disease: Contributions and global trends.帕金森病的分子遗传学:贡献与全球趋势。
J Hum Genet. 2023 Mar;68(3):125-130. doi: 10.1038/s10038-022-01058-5. Epub 2022 Jul 11.
5
Role of the mtDNA Mutations and Mitophagy in Inflammaging.线粒体 DNA 突变与自噬在炎症衰老中的作用。
Int J Mol Sci. 2022 Jan 25;23(3):1323. doi: 10.3390/ijms23031323.
6
PARKIN modifies peripheral immune response and increases neuroinflammation in active experimental autoimmune encephalomyelitis (EAE).PARKIN 改变活跃的实验性自身免疫性脑脊髓炎(EAE)中的外周免疫反应并增加神经炎症。
J Neuroimmunol. 2021 Oct 15;359:577694. doi: 10.1016/j.jneuroim.2021.577694. Epub 2021 Aug 12.
7
Blood-Brain Barrier Leakage Is Increased in Parkinson's Disease.帕金森病中血脑屏障渗漏增加。
Front Physiol. 2020 Dec 22;11:593026. doi: 10.3389/fphys.2020.593026. eCollection 2020.
8
Intestinal infection triggers Parkinson's disease-like symptoms in Pink1 mice.肠感染引发 Pink1 小鼠类似帕金森病的症状。
Nature. 2019 Jul;571(7766):565-569. doi: 10.1038/s41586-019-1405-y. Epub 2019 Jul 17.
9
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.帕金森病与自身免疫性疾病之间的全基因组多效性
JAMA Neurol. 2017 Jul 1;74(7):780-792. doi: 10.1001/jamaneurol.2017.0469.
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Myeloperoxidase-immunoreactive cells are significantly increased in brain areas affected by neurodegeneration in Parkinson's and Alzheimer's disease.髓过氧化物酶免疫反应细胞在帕金森病和阿尔茨海默病神经退行性变受影响的脑区显著增加。
Cell Tissue Res. 2017 Sep;369(3):445-454. doi: 10.1007/s00441-017-2626-8. Epub 2017 May 2.