Lampl Stephan, Gurunathan Deepa, Krithikadatta Jogikalmat, Mehta Deepak, Moodley Desigar
Department of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Department of Pediatric Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
JMIR Res Protoc. 2023 Nov 1;12:e51505. doi: 10.2196/51505.
There is a tendency nowadays to restore large defects in primary dentition with pediatric crowns instead of conventional restorations. Thus, understanding the factors contributing to the survival or failure of dental crowns in pediatric dentistry is essential for optimizing treatment outcomes.
The primary objective of this protocol is to outline the methodological approach for analyzing data from observational studies and randomized controlled trials to investigate reasons for the failure of dental crowns in primary teeth and to compute their survival and failure rates.
A comprehensive literature review will be performed in electronic databases, including PubMed (MEDLINE), Cochrane, Embase, and Web of Science. As per predefined inclusion criteria, we will include observational studies (prospective clinical studies) and randomized clinical trials that have an English abstract and involve children aged 1-10 years undergoing crown restorations. Two independent reviewers will independently screen all retrieved records and full-text articles and extract data. The study's methodological quality will be appraised using suitable tools. Assessments of publication bias will be performed using funnel plots. The findings will be described qualitatively for the systematic review. If possible, a meta-analysis will be performed to estimate failure rates by dividing the number of failures by the total exposure time. A Poisson regression model, assuming constant event rates, will be used to compute 3-year and 5-year survival proportions. The Pearson goodness-of-fit statistics will be used to assess the heterogeneity of the model. A P value <.05 will be considered significant. All analyses will be performed using R Statistical software (version 4.1.2; R Core Team).
This systematic review and synthesis aim to assess the survival and failure rates of dental crowns in pediatric dentistry. By following this rigorous methodology, we seek to provide valuable insights into the factors contributing to the success or failure of these restorations. The results of our full review will have implications for pediatric dentists, researchers, and policy makers, helping to improve dental care for children.
This systematic review protocol helps in establishing a thorough approach for reviewing failures in pediatric crowns. By following this methodology, standardization and transparency of the process as well as accountability for the stated methods and outcomes will be ensured. The findings of this review and analysis will provide useful data on the survival of crowns to pediatric dentists and researchers.
PROSPERO CRD42023442266; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=442266.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/51505.
如今，用儿童牙冠修复乳牙的大缺损而非传统修复方法已成为一种趋势。因此，了解影响儿童牙科中牙冠存活或失败的因素对于优化治疗效果至关重要。
本方案的主要目的是概述分析观察性研究和随机对照试验数据的方法，以调查乳牙牙冠失败的原因并计算其存活率和失败率。
将在电子数据库中进行全面的文献综述，包括PubMed（MEDLINE）、Cochrane、Embase和Web of Science。根据预先定义的纳入标准，我们将纳入有英文摘要且涉及1至10岁接受牙冠修复儿童的观察性研究（前瞻性临床研究）和随机临床试验。两名独立的评审员将独立筛选所有检索到的记录和全文文章并提取数据。将使用合适的工具评估研究的方法学质量。将使用漏斗图进行发表偏倚评估。将对系统评价的结果进行定性描述。如果可能，将进行荟萃分析，通过将失败数除以总暴露时间来估计失败率。将使用假设事件率恒定的泊松回归模型计算3年和5年生存率。将使用Pearson拟合优度统计量评估模型的异质性。P值<.05将被视为具有统计学意义。所有分析将使用R统计软件（版本4.1.2；R核心团队）进行。
本系统评价和综合分析旨在评估儿童牙科中牙冠的存活率和失败率。通过遵循这种严谨的方法，我们旨在为这些修复体成功或失败的影响因素提供有价值的见解。我们全面审查的结果将对儿童牙医、研究人员和政策制定者产生影响，有助于改善儿童的牙科护理。
本系统评价方案有助于建立一种全面的方法来审查儿童牙冠的失败情况。通过遵循这种方法，将确保过程的标准化和透明度以及对所述方法和结果的问责制。本综述和分析的结果将为儿童牙医和研究人员提供有关牙冠存活的有用数据。
PROSPERO CRD42023442266；https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=442266。
国际注册报告标识符（IRRID）：PRR1-10.2196/51505。
